Nanoemulsion Market Overview
The Global Nanoemulsion Market report analyzes the global market size, shares, recent trends, competitive intelligence, and future market outlook. Nanoemulsion is a type of emulsion with droplet sizes in the nanometer range, offering improved stability and bioavailability. The market is driven by the increasing demand for nanoemulsion-based products in the pharmaceutical, cosmetics, and food industries. In America, the Global Nanoemulsion Market is experiencing rapid growth. Key players in the market include Company I, Company J, Company K, and other prominent players.
Nanoemulsions are nano-sized emulsions, which are generally manufactured for improving the delivery of active pharmaceutical ingredients. These are thermodynamically stable isotopic systems in which two immiscible liquids are mixed to form a single phase through an emulsifying agent, i.e., surfactant and the co-surfactant. The droplet size of nanoemulsion fall in the range of 20-200 nm. These carriers are solid spheres, and their surface is amorphous and lipophilic with a negative charge.
Three types of nanoemulsions can be formed: a) oil in water nanoemulsion in which oil is dispersed in a continuous aqueous phase b) water in oil nanoemulsion in which water droplets are dispersed in the continuous oil phase, and c) bi-continuous nanoemulsions. Nanoemulsions can be used as a substitute for liposomes and vesicles, improve the bioavailability of drugs, helps in taste masking, and help to solubilize lipophilic drugs. The main components of nanoemulsions are oil, emulsifying agents, and aqueous phases.]
Nanoemulsion Market Scope
Metrics | Details |
Market CAGR | 9.4% |
Segments Covered | By Type, By Application, and By Region |
Report Insights Covered | Competitive Landscape Analysis, Company Profile Analysis, Market Size, Share, Growth, Demand, Recent Developments, Mergers and acquisitions, New Product Launches, Growth Strategies, Revenue Analysis, and Other key insights. |
Fastest Growing Region | Asia Pacific |
Largest Market Share | North America |
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Nanoemulsion Market Dynamics
The global nanoemulsion market is observed to see significant demand in various industries. It has seen exponential growth in the improvement in the delivery of active pharmaceutical ingredients(API). Also, the increase in the need for various types of technologies in the generation of nanoemulsion drives the growth of the nanoemulsion market.
Increasing research and development activities will drive the market growth
In recent times the rise in the global population has urged the food demand. In turn, this is anticipated to raise the demand for new types of emulsifiers in the food industry. Also, the increase in various types of technologies in the generation of nanoemulsion drives the growth of the nanoemulsion market. Nanoemulsion enables targeted delivery and hence made a revolution in the targeted treatment of many cancer diseases. Though nanoemulsions are being explored for cancer treatment, prevention, and detection, their exact dosages and long-term effects on cancer therapy are yet to be studied.
Recently, a new technological advancement of theranostic nanomedicine is considered promising for personalized medicine. Of this, celecoxib loaded near-infrared labeled perfluorocarbon nanoemulsion on three levels of scales was produced by the micro fluidization technique. There was no significant result of nanoemulsion scales on cell toxicity and pharmacological effects. Research in natural products has captured a vital role in the food, drug, and cosmetic, commercial arena. Of this accord, herbal essential oil-based nanoemulsions are pondered with great interest in recent years owing to their unique and versatile properties and applications.
Nanoemulsion witnessing a steep demand from the cosmetic industry
Nanoemulsions of plant-based bioactive compounds such as flavonoids and polyphenols improve the cosmeceutical value due to very slight toxicity. A multiple nanoemulsion of genistin coloaded with tocomin offers skin protection from U.V. Nanoemulsions of Aloe vera extracts showed skin rejuvenation and anti-wrinkle activity. A rice bran oil nanoemulsion could be used as a moisturizer with anti-aging activity. Nanoemulsions of D-Limonene and tocopherol were used in skincare applications. Vitamin E-enriched palm oil nanoemulsions showed improved stability and are used for further applications. Genistein-loaded nanoemulsion enhances the delivery of isoflavones to the skin with good skin-protecting activity. A pomegranate seed oil nanoemulsion demonstrated increased skin protection against photodamage with improved antioxidant activities today, almost all the major cosmetics manufacturers use nanomaterials in their products. Today almost all major cosmetic manufacturers use nanoparticles in their products. For instance, the world's largest company L'Oréal is devoting about $600 million and ranks 6th in the U.S. in the number of nanotech-related patents.
Side effects associated with the high cost of nanoemulsions
Nanoemulsion technology or in general any process which involves nanoemulsions is costly compared to any other emulsifying procedures involved in the generation of food. This makes nano-emulsifying methods counted as a premium product series. Thus high production cost of emulsifiers and the rise in the price of new machines hinder the growth of the market.
COVID-19 Impact on Market Growth
COVID-19 is expected to have a positive effect on the global nanoemulsion market. Nanoemulsions are used extensively as vaccine carriers and adjuvants. In vaccines, nanoemulsions are used as they offer various advantages like increasing the surface area of an antigen, slow release of an antigen, uniform dispersion, and good vaccine stability. In a research article appearing in the September 2020 issue of News-Medical.Net, researchers stated that a potential COVID-19 vaccine could include a cationic nanoemulsion-based system.
Pulmonary Surfactant (P.S.) assisted antiviral drug delivery by nanoemulsion system could be another effective approach for the treatment of COVID-19. The use of functional excipients like Pulmonary Surfactant (P.S.) and Surfactant Proteins (S.P.s) in the formulation of the antiviral drug-loaded nanoemulsion system can improve the treatment of coronavirus infection. Pea protein's nanoemulsion may serve as a shuttle for vitamin D fortification during the coronavirus pandemic.
Nanoemulsion Market Segment Analysis
Based on type, the global nanoemulsion market is divided into small-molecule surfactants, protein-stabilized emulsions, and polysaccharide
The small-molecule surfactant segment is expected to grow at the fastest CAGR during the forecast period (2024-2031)
Small-molecule surfactants lie between the size of 0–100 nm. These small size particles prevent creaming. As a result, nanoemulsions often have satisfactory long-term stability. Consequently, the use of synthetic small-molecule TLRa has significant advantages because they are well-defined discrete molecules, which can be chemically modified to modulate their physicochemical properties.
Based on applications, the global nanoemulsion market is divided into the food & beverage, cosmetics, and pharmaceutical industries
The pharmaceutical industries are expected to dominate the global nanoemulsion market segment in the forecast period
Vaccines play a significant role in treating various chronic and infectious diseases, which gained more importance in recent years. An enormous number of biopharmaceutical companies are using nanoemulsion formulations in the development of vaccines. Nanoemulsions, emulsions sized between 20-200 nm with narrow distributions, offer several advantages for topical and transdermal delivery of pharmaceutical agents including controlled droplet size, the ability to efficiently dissolve lipophilic drugs, enhanced skin permeation and extended release of lipophilic and hydrophilic drugs. Moreover, they exert good sensorial and physical properties such as complete dispersion on skin and skin hydration in cosmetic products. In June 2019, BlueWillow Biologics, Inc., a nanotechnology-based vaccine manufacturer, announced that it had received a United States patent for an intranasal NanoVax anthrax vaccineNanoemulsions provide enhanced transdermal permeation of drugs which in turn increases plasma concentration profile and bioavailability of drugs. There are different modes for the organization of nanoemulsion-based meds. Oral and parenteral podes are very well known, albeit different techniques (for instance, through eye drops) are likewise famous—organizations working in the market team up for novel item improvement. For instance, in May 2018, Ascendia Pharmaceuticals, a forte drug organization, declared a coordinated effort with K.C. Pharmaceuticals to advance over-the-counter (OTC) clean ophthalmic drop prescriptions. Drives, for example, are probably going to support market development and advancement.
Source: DataM Intelligence Analysis (2023)
Nanoemulsion Market Geographical Share
North America is expected to dominate the market over the forecast period
A high level of research and development on nanoemulsion drug discovery and technological developments is fueling the market. A high number of chronic diseases and advanced healthcare structure and government initiatives and an increase in the legalization of cannabis products are some of the drivers for the increase in its market. Innovative product developments in this region are expected to have a positive effect on its market.
On the other hand, Asia-Pacific is going to follow North America in the forecast period with its developing technology and health issues of the population. Especially China and India in the coming days.
Nanoemulsion Market Companies and Competitive Landscape
The global nanoemulsion market is moderately competitive with the presence of local as well as global companies. Some of the key players which are contributing to the growth of the market include Keystone Foods, Frutarom Group, WILD Flavors, Specialty Ingredients, Nestle S.A., Covaris Inc., AQUANOVA AG, Jamba, Unilever Group, Shemen Industries Ltd, Latitude Pharmaceuticals Inc, Sanofi Pharma. The major players are adopting several growth strategies such as product launches, acquisitions, and collaborations, which are contributing to the growth of the Nanoemulsion market globally.
Sanofi Pharma
Overview: Sanofi Pharma, Sterling Winthrop, and Bristol-Myers Squibb have entered into a significant new collaborative agreement covering the joint development of two of Sanofi's cardiovascular products. Sanofi said that the link-up with a cardiovascular specialist such as Bristol-Myers Squibb would enhance the potential of the two compounds and accelerate their progress onto the market.
The two compounds are clopidogrel, an antithrombotic agent for preventing transient ischemic attacks, stroke, myocardial infarction, and peripheral artery disease. Clopidogrel was approved in 1997. Clopidogrel is one of the leading antithrombotic drugs in use today, and as recently as 2011 was the second best-selling drug product globally, achieving over $7 billion in sales that year. Using its EmulSol technology, Ascendia has developed a novel oil-in-water nanoemulsion formulation of clopidogrel. EmulSolTM is Ascendia's proprietary technology for the production of novel oil-in-water nanoemulsions. This nanoemulsion used technology helps to overcome the barriers to developing bioavailable dosage forms.
Product Portfolio: Sanofi engages in the research and development, manufacturing, and marketing of pharmaceutical drugs principally in the prescription market, but the company also develops over-the-counter medication. The company covers seven major therapeutic areas: cardiovascular, central nervous system, diabetes, internal medicine oncology, thrombosis, and vaccines.
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