Hydroxyapatite Market

SKU: DMMD505 | Last Updated On: Jan 19 2023 | Available Formats

> Hydroxyapatite Market Expected to reach a high CAGR of 7.3% By 2023-2030:

Hydroxyapatite Market is segmented By Type (Nano-sized, Micro-sized, Greater than Micrometers), By Application (Orthopedic, Dental Care, Plastic Surgery, others), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2023-2030.

Hydroxyapatite Market reached USD million in 2022 and is expected to record significant growth by reaching up to USD million by 2030, growing at a CAGR of 7.3% during the forecast period (2023-2030). Hydroxyapatite (HA or HAP) of biologic (coral, bovine or marine algae-derived) or synthetic origin is utilized for bone regeneration and repair in the form of granules, blocks and scaffolds alone or in composite with polymers or other ceramics or as coatings on orthopedic or dental implants. The products are commercially available for bone repair, replacement and augmentation and scaffolds in tissue engineering for bone regeneration. The development of hydroxyapatite as a bone substitute material is its compositional closeness to bone minerals. HA is also utilized as an abrasive to roughen the surfaces of metal implants and as source material for depositing bioactive coatings on orthopedic and dental implants. The materials are also suitable for application as transfection agents, medication transporters and percutaneous devices. 

As per DataM Intelligence, Hydroxyapatite Market study analysis offers an in-depth outlook on the market containing quantitative and qualitative data. It gives an outlook and forecast of the global market based on market segmentation. It also provides global Hydroxyapatite Market size, and growth, along with the latest trends, opportunities, and forecast till 2029 for the global market with esteem to major countries such as the United States, Canada, Brazil, Germany, Italy, Spain, United Kingdom, Russia, European countries, United Arab Emirates, Saudi Arabia, South Africa, Japan, China, India, South Korea, Australia, and rest of the countries over the globe.

Among all regions, the North American region is expected to hold the largest share of the global market over the forecast period. Hydroxyapatite Market in the United States and Canada produces the utmost share. Whereas the European Hydroxyapatite Market is projected to continue its presence globally during the period of 2022- 2029.

Hydroxyapatite Market Report Scope



Market CAGR


Segments Covered

By Type, By Application, and By Region

Report Insights Covered

Competitive Landscape Analysis, Company Profile Analysis, Market Size, Share, Growth, Demand, Recent Developments, Mergers and acquisitions, New Product Launches, Growth Strategies, Revenue Analysis, and Other key insights.

Fastest Growing Region

Asia Pacific

Largest Market Share 

North America

Market Dynamics

The market is driven by the expanding demand for hydroxyapatite in cosmetics dentistry and the increasing adoption of hydroxyapatite as a bone graft substitute. The rising concerns associated with the toxic effects of hydroxyapatite may hamper growth.

Growing demand for cosmetic dentistry 

Cosmetic dentistry enhances dental health, resulting in a complete sense of well-being that includes feeling well and looking good. Following in the footsteps of cosmetic surgery, advancements in cosmetic dentistry have cleared the path for more permanent facial modifications that go far beyond straightening crooked teeth. Aesthetic dental procedures include removing tooth stains, professional teeth whitening, reshaping teeth, filling gaps and fissures, inserting crowns, veneers, bridges, dentures, dental implants and oral restorations through dental fillings.

As per the American Academy of Cosmetic Dentistry (AACD), about % of women in U.S. aged 30 and above choose cosmetic dentistry due to the rising need for treatment of dental disorders with age. Hydroxyapatite is one of the most researched biomaterials in the medical profession due to its biocompatibility and role as the primary constituent of the mineral part of bone and teeth. In terms of restoration and prevention, nano-hydroxyapatite has strong remineralizing effects on early enamel lesions, which is unquestionably superior to traditional fluoride and has good results on tooth sensitivity. Because of its unique qualities, including chemically attaching to bone and encouraging bone development directly impacting osteoblasts, nano-HA has been widely used in the therapeutic sector in periodontology and oral and maxillofacial surgery.

As the demand for cosmetic dentistry skyrockets and hydroxyapatite is a premier material in the respective field, the experienced demand growth for cosmetic dentistry could trigger demand and production growth in the global hydroxyapatite market. Thus the respective factor could be considered a major market driver.

Increasing adoption of hydroxyapatite as a bone graft substitute 

Bicycling, ice hockey, snow skiing, baseball, basketball, skateboarding and other comparable activities are becoming increasingly popular among children and adults. Given the prevalence of major sports injuries, intervention by sports injury specialists is frequently required for treating a damaged or injured ankle, hip, knee, wrist, elbow or shoulder joint, thereby boosting the demand for bone grafts and substitutes. 

Bone resorption is irreversible after tooth loss, leaving the area with insufficient bone volume for effective implant treatment. Bone grafting is a widely approved technique for one out of four dental implants since it is the only way to recover the dental bone loss. Over the years, research and development in materials, design and fabrication methods have expanded to create successful and long-lasting dental implants for tooth replacement. Since HA offers incomparable advantages in promoting bone growth, the growing number of grafting procedures could result in an exponential upward demand for HA. As a result, the abovementioned factor could be considered a major market driver.

Concerns associated with toxic effects of hydroxyapatite 

Nano-hydroxyapatite has been mainly used as an oral care ingredient, with numerous products used to treat dental hypersensitivity and enamel remineralization. Despite the promising results, the European Scientific Committee on Consumer Safety (SCCS) has raised regulatory and safety concerns about using hydroxyapatite nanoparticles in oral care products. 

In its nanoparticulate form, such as a nanoparticle or as a nanoparticulate bone substitute material or following abrasion from a hydroxyapatite-coated metal implant, certain characteristics of HA particles may influence cytotoxicity. Concerns about the potentially detrimental effects of nano-hydroxyapatite have been raised in light of the current debate on the safety of nanoparticles. In 2016, there was a debate in U.S. over the hazards of nano-calcium phosphate in infant food.

COVID-19 Impact Analysis

The COVID-19 outbreak has majorly impacted various services & manufacturing businesses due to the implementation of lockdowns and reduced operational capacities to stop the virus's spread, causing the economy to suffer. As per the World Bank, the epidemic has lowered investments and operational interruptions in business & supply networks. Furthermore, due to the COVID-19 pandemic, many variables produced a significant downward rift in the global hydroxyapatite market.

Another pandemic's most significant impact on the market is the supply chain, which tarnishes raw materials and the selling of finished goods due to a large demand-supply mismatch caused by raw materials' unavailability and disruption of production operations. The pandemic's significant influence on the global hydroxyapatite business might be explained further by interruptions and downfalls observed in key end-user sectors. For instance, hydroxyapatite is used to substitute bone grafts in orthopedic operations. These surgeries are elective and most were postponed or canceled during the COVID-19 pandemic. The respective factor resulted in a significant decrease in demand for hydroxyapatite. 

Segment Analysis

By type, the hydroxyapatite market is segmented into nano-sized, micro-sized and greater than micrometers.

Hydroxyapatite acts as the main component of teeth and bone

One phosphate and one hydroxyl group make up hydroxyapatite, the mineral form of calcium apatite. It is a main component of teeth and has a higher stiffness and remineralization rate than saliva. Increased gap healing between bone and hydroxyapatite, faster bone healing at the bone-implant interface and corrosion inhibition are some of the benefits of hydroxyapatite coatings in orthopedic implants and dental care products. As a result, producers are substituting nano-hydroxyapatite coatings for traditional titanium plasma spray coatings.

Owing to the closeness to Hydroxyapatite (HA) in real bone, hydroxyapatite nanoparticles (HANP) have a variety of biomedical applications, including as a bone grafting material. Because HANP is made up of nanoparticles (NP), it can circulate throughout the body and collect mostly in the lungs, liver and spleen. As a result, HAp nanoparticles have become increasingly popular in recent years and considerable work has gone into developing a variety of synthetic methods that include both scientifically and economically novel aspects.

Geographical Analysis

The growing elderly population in Asia-Pacific

Asia-Pacific is the fastest-growing region in the hydroxyapatite market. Asia Pacific market is growing due to increased demand for Hydroxyapatite from China and South Korea. Furthermore, the Asia-Pacific aging population, rising middle-class disposable income and expanding public awareness of the benefits of dental bone grafting and bone grafting over traditional therapies create a tremendous opportunity for hydroxyapatite manufacturers.

For instance, the elderly population in Asia-Pacific is increasing at an unprecedented rate and the area is at the forefront of the global population aging crisis. One in every four persons in Asia-Pacific will be over 60 years old by 2050. Between 2010 and 2050, the region's population of senior adults (those over 60) will treble, reaching about 1.3 billion individuals. Thus, improving the elderly population increases bone-related abnormalities, improving the demand for the hydroxyapatite market in the region.

Competitive Landscape 

The global market is highly competitive with several international and local markets. Product diversification, revenue generation and opportunities intensify the market competition. The major companies are focusing on research efforts to develop more effective products at lower costs to gain wider adoption and grow the market.

Major global market companies include Fluidinova, SofSera Corporation, Berkeley Advanced Biomaterials, Taihei Chemical Industrial Co., Ltd., Sigmagraft, CAM Bioceramics B.V., Granulab, Bionnovation, Evonik Industries AG and Merz Pharma GmbH & Co.KGaA.


Overview: The company was founded in 1993 as a small development company in Bauru. It was initially founded in the name of Kunzel Brasil Equipamentos Odontológicas Ltda. Bioinnovation is involved in offering solutions related to the replacement of dental elements and tissue reconstruction. The company has 15 years of expertise & research and sold more than 1.5 million implants across the globe. It also sold more than 4 tons of bone grafts and more than 15 kilometers of membranes and barriers. The product, services and training of Bioinnovation are available in 30 countries across the globe. In 2020, the company started the construction of a new Bioinnovation plant with a special focus on the production and development of products focused on bone regeneration. 

Product Portfolio: The company provides hydroxyapatite which is 100% synthetic, more than 95 percent phase purity, biocompatible and allows the monetarization of osteointegration. Bioinnovation provides the product in different codes which have different compositions.

Key Development: In September 2021, the company used GS1 standards to identify dental implants and other products. It will reduce order fulfillment errors and helps in achieving end-to-end product traceability throughout its global supply chain, thereby improving productivity and inventory management.

Report suggestion:

  • Global Plastic Surgery Market
  • Global Orthopedic Biomaterials Market
  • Global Bone Cement Market

Trending Topics

Plastic Surgery Market

Orthopedic Biomaterials Market

Bone Cement Market 

Did not find what you were looking for?Every 7 out of 10 customers request tailored reports. Get yours today!
We collate your requirements.
Our global research team is put into action.
We deliver, and make sure your endeavour is a success!

Buy This Report

20% Discount Applied*

Note*: For "Bundle/Bulk" Subscription of Reports,
please contact: [email protected]

Get your free sample proposal with a single click!