Global Orthobiologics Market - Size, Share and Forecast (2019-2026)

SKU: DHC81 | Published On: 2019-05-17 | Available Formats

Orthobiologics Market

Global Orthobiologics Market

The Global Orthobiologics market was valued at USD XX million in 2018 and expected to grow at a CAGR of XX% to reach a market value of USD XX million by 2026.

Orthobiologics, also called regenerative cellular therapies, are biological substances that can be used in helping injuries to heal more quickly. They are used to improve the healing of fractures, injured muscles, tendons, and ligaments. Orthobiologics are made from substances that naturally occur in the body, and when used in high concentration, they may assist in speed up the healing process. Orthobiologics find their use for the treatment of conditions such as spinal fusion, fracture recovery, and others. These are also available for the knee, hip, ankle, spine, wrist, and other body parts. The various products in Orthobiologics include bone grafts, platelet-rich plasma (PRP), autologous conditioned serum, stem cells, and growth factors.

Global Orthobiologics Market – Market Dynamics

The global market for the orthobiologics Market is primarily driven by the rising geriatric population, prevalence of obesity, and increasing incidence of orthopedic disorders and musculoskeletal diseases. According to the United Nations (UN), an estimated 10% - 15% of all adults aged over 60 have some degree of Osteoarthritis, with the prevalence higher in women than men. According to the World Health Organization (WHO), 2016, more than 1.9 billion adults aged 18 years and older were overweight, of these over 650 million adults were obese. Moreover, the rise in several sports-related accidents and road accidents and the adoption of minimally invasive surgeries further propel the market. According to WHO, in 2018, approximately 37.3 million falls are severe enough to require medical attention occurred. The most substantial morbidity is arising in people aged 65 years or older. According to Anterior Cruciate Ligament (ACL) Injury Prevention, an article published in 2017, it was estimated that around 350,000 ACL reconstructions are performed annually in the USA and despite a surgical repair, approximately 79% of those individuals develop knee osteoarthritis, and 20% suffer re-injury within two years. 

However, the high cost of procedures, post-surgery complications, and stringent regulatory approval may hinder market progress. 

Global Orthobiologics Market – Segment Analysis

By Product, the global Orthobiologics market is segmented into Bone Morphogenetic Proteins (BMP), Demineralized Bone Matrix (DBM), Synthetic Bone Substitutes, Viscosupplements, Allografts, Stem cell, and others. Viscosupplements segment holds the most significant market share in Orthobiologics. It can be attributed to the high adoption rate of as it is widely available and favorable reimbursement policies. Viscosupplements advantage of being less-invasive, pain reduction, and having fewer side effects make it an attractive market. Moreover, the presence of strong product pipeline portfolios is expected to boost market development.

By Application, the global Orthobiologics market is segmented into Osteoarthritis & Degenerative Arthritis, Spinal Fusion, Fracture Recovery, Soft Tissue Injuries, and Maxillofacial & Dental Applications. The Osteoarthritis & degenerative arthritis sector occupies the most significant Orthobiologics market share. It can be attributed to the presence of huge geriatric population, who are more prone to osteoarthritis. The United Nations estimated that by 2050 people aged over 60 will account for more than 20% of the world’s population, of which 15-20% (around 130 million people) are estimated to have symptomatic osteoarthritis. The spinal fusion segment is expected to be the fastest growing market share owing to the rising prevalence of spinal cord injuries, sports-related injuries, and accidents.

Global Orthobiologics Market– Geographical Analysis

North America is the dominant share in the global Orthobiologics market, and it is primarily attributed to factors such as the increasing incidence of spinal disorders, rise in the geriatric population and obese population, and higher awareness about minimally invasive surgeries. Moreover, its broad base of the patient population and the established healthcare infrastructure and the rising disposable income and higher investment in R&D activities contribute to the growth of North America’s share. According to the National Spinal Cord Injury Database, 2018, the number of people with spinal cord injury (SCI) living in the United States is currently estimated to be approximately 288,000 persons. Moreover, about 20.7 million adults in the United States have degenerative joint disease. According to the American Academy of Orthopaedic Surgeons (AAOS), an estimated 4.7 million Americans have undergone total knee arthroplasty (TKA), and 2.5 million have undergone total hip arthroplasty (THA) and are living with implants. Additionally, favorable reimbursement policies for soft tissue healing and fusion enhancement products are expected to boost the regional market share.

Asia-Pacific region is expected to be the fastest growing market during the forecast period, owing to the region’s rapidly improving healthcare infrastructure and the presence of a broad base of the target population. According to the International Osteoporosis Foundation (IOF), osteoporosis affects almost 70 million Chinese over the age of 50 and causes some 687,000 hip fractures in China each year.

Global Orthobiologics Market– Competitive Analysis

Key players are adopting strategies such as mergers and acquisitions, partnerships, and regional expansion to stand out as strong competitors in the market. New product drug, strong clinical pipeline and increasing R&D are other ways the leading players improve their market presence.

In May 2019, Regenacell Therapy launched the Lipo-Pro System, a new and innovative adipose harvesting and processing device. This unique offering allows for the sourcing of adipose aspirate and subsequent adipose graft preparation at point of care by retaining the cellular component of both the graft and infranatant while removing of the acellular components of oil and remaining infranatant. It will provide a tool that allows physicians conducting autologous injection therapies.

In May 2019, Anika Therapeutics, a global, integrated orthopedic and regenerative medicines company specializing in therapeutics based on its proprietary hyaluronic acid ("HA") technology, announced plans to showcase its regenerative medicine and orthobiologics portfolio at the 12th Biennial International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS) Congress.

In October 2018, Bone Therapeutics, a bone cell therapy company addressing high unmet medical needs in orthopaedics and bone diseases, announced the results of the first efficacy study of the Company’s enhanced viscosupplement, JTA-004, in patients with moderate symptomatic knee osteoarthritis, supporting future clinical development of the product. JTA-004 is a patented, non-cellular viscosupplement product for the treatment of knee osteoarthritis (KOA), which Bone Therapeutics has been developing in parallel with its core cell therapy pipeline and addressing its mission of bringing innovative solutions to orthopaedic conditions.

In July 2018, Bioventus, a global leader in orthobiologic solutions, entered into a definitive agreement to divest its next generation bone morphogenetic protein (BMP) development program to a new company formed by Viscogliosi Brothers (VB), a private equity investment firm focused on developing innovative neuromusculoskeletal technologies. Bioventus acquired the exclusive, worldwide license to the BMP portfolio of development programs and associated intellectual property from Pfizer, in 2013. The portfolio, which will now be sold to VB, includes the next-generation BMP in development, as well as a BMP program for soft tissue indications.


Key Takeaways:

· The global market for the Orthobiologics Market is primarily driven by the rising geriatric population, prevalence of obesity, and increasing incidence of orthopedic disorders and musculoskeletal diseases. 

· The Osteoarthritis & degenerative arthritis sector occupies the most significant Orthobiologics market share. It can be attributed to the presence of huge geriatric population, who are more prone to Osteoarthritis.

· North America is the dominant share in the global Orthobiologics market, and it is primarily attributed to factors such as the increasing incidence of spinal disorders, rise in the geriatric population and obese population, and higher awareness about minimally invasive surgeries.

· Strong clinical pipeline and increasing R&D are ways key players improve their market presence. For instance, in October 2018, Bone Therapeutics announced the results of the first efficacy study of the Company’s enhanced viscosupplement, JTA-004, in patients with moderate symptomatic knee osteoarthritis, supporting future clinical development of the product.


Why Purchase the Report?

· Visualize the composition of the global Orthobiologics Market across each indication, in terms of Application and End User options, highlighting the key commercial assets and players.

· Identify commercial opportunities in global Orthobiologics Market by analyzing trends and co-development deals.

· Excel data sheet with thousands of data points of the global Orthobiologics Market - level 4/5 segmentation.

· PDF report with the most relevant analysis cogently put together after exhaustive qualitative interviews and in-depth market study.

· Type mapping in excel for the key Services of all major market players


Target Audience:

·        Equipment Suppliers/ Buyers

·        Type Providers/ Buyers

·        Industry Investors/Investment Bankers

·        Education & Research Institutes

·        Research Professionals

·        Emerging Companies

·        Manufacturers



1. Global Orthobiologics Market -Scope and Methodology

1.1. Research Methodology

1.2. Scope of the market

2. Global Orthobiologics Market -Key Trends and Developments

2.1. Key Trends and Developments

3. Global Orthobiologics Market – Executive Summary

3.1. Market Snippet By Product

3.2. Market Snippet By Application

3.3. Market Snippet By End User

3.4. Market Snippet by Region

3.5. DataM CLO Scenario

4. Global Orthobiologics Market – Market Dynamics

4.1. Market impacting factors

4.2. Drivers

4.2.1. Rise in incidence of orthopedic diseases & injury

4.2.2. Rising geriatric and obese population

4.2.3. Increase in sports injuries

4.2.4. Driver 4

4.3. Restraints

4.3.1. High cost of Orthobiologics product

4.3.2. Stringent approval process

4.3.3. Restraint 3

4.4. Opportunity

4.5. Impact analysis

5. Global Orthobiologics Market – Industry Analysis

5.1. Porter's five forces analysis

5.2. Supply chain analysis

5.3. Regulatory analysis

5.4. Patent analysis

5.5. Technological advances

5.6. Epidemiology

6. Global Orthobiologics Market – By Product

6.1. Introduction

6.2. Market size analysis, and y-o-y growth analysis (%), by Product segment

6.3. Market attractiveness index, by Product segment

6.4. Bone Morphogenetic Proteins (BMP)

6.4.1. Introduction

6.4.2. Market size analysis, and y-o-y growth analysis (%)

6.5. Demineralized Bone Matrix (DBM)

6.6. Synthetic Bone Substitutes

6.7. Viscosupplements

6.8. Allografts

6.9. Stem cell 

6.10. Others

7. Global Orthobiologics Market – By Application

7.1. Introduction

7.2. Market size analysis, and y-o-y growth analysis (%), by Application segment

7.3. Market attractiveness index, by Application segment

7.4. Osteoarthritis & Degenerative Arthritis

7.4.1. Introduction

7.4.2. Market size analysis, y-o-y growth analysis (%)

7.5. Spinal Fusion   

7.6. Fracture Recovery     

7.7. Soft Tissue Injuries   

7.8. Maxillofacial & Dental Applications

8. Global Orthobiologics Market – By End User

8.1. Introduction

8.2. Market size analysis, and y-o-y growth analysis (%), by End User segment

8.3. Market attractiveness index, by End User segment

8.4. Hospitals

8.4.1. Introduction

8.4.2. Market size analysis, y-o-y growth analysis (%)

8.5. Orthopedic Clinics

8.6. Dental Clinics

8.7. Others

9. Global Orthobiologics Market – By Region

9.1. Introduction

9.2. Market Size Analysis, And Y-O-Y Growth Analysis (%), By Region

9.3. Market Attractiveness Index, By Region

9.4. North America

9.4.1. Introduction

9.4.2. Key region-specific dynamics

9.4.3. Market Size Analysis, And Y-O-Y Growth Analysis (%), By Product

9.4.4. Market Size Analysis, And Y-O-Y Growth Analysis (%), By Application

9.4.5. Market Size Analysis, And Y-O-Y Growth Analysis (%), By End User

9.4.6. Market Size Analysis, And Y-O-Y Growth Analysis (%), By Countries

9.4.6.1.U.S.

9.4.6.2.Canada

9.4.6.3.Mexico

9.5. Europe

9.5.1.Introduction

9.5.2.Key Region-Specific Dynamics

9.5.3.Market Size Analysis, And Y-O-Y Growth Analysis (%), By Product

9.5.4.Market Size Analysis, And Y-O-Y Growth Analysis (%), By Application

9.5.5.Market Size Analysis, And Y-O-Y Growth Analysis (%), By End User

9.5.6.Market Size Analysis, And Y-O-Y Growth Analysis (%), By Countries

9.5.6.1.Germany

9.5.6.2.U.K.

9.5.6.3.France

9.5.6.4.Italy

9.5.6.5.Spain

9.5.6.6.Rest of Europe

9.6.South America

9.6.1.Introduction

9.6.2.Key Region-Specific Dynamics

9.6.3.Market Size Analysis, And Y-O-Y Growth Analysis (%), By Product

9.6.4.Market Size Analysis, And Y-O-Y Growth Analysis (%), By Application

9.6.5.Market Size Analysis, And Y-O-Y Growth Analysis (%), By End User

9.6.6.Market Size Analysis, And Y-O-Y Growth Analysis (%), By Countries

9.6.6.1.Brazil

9.6.6.2.Argentina

9.6.6.3.Rest of South America

9.7. Asia Pacific

9.7.1. Introduction

9.7.2. Key Region-Specific Dynamics

9.7.3. Market Size Analysis, And Y-O-Y Growth Analysis (%), By Product

9.7.4. Market Size Analysis, And Y-O-Y Growth Analysis (%), By Application

9.7.5. Market Size Analysis, And Y-O-Y Growth Analysis (%), By End User

9.7.6. Market Size Analysis, And Y-O-Y Growth Analysis (%), By Countries

9.7.6.1.China

9.7.6.2.India

9.7.6.3.Japan

9.7.6.4.Australia

9.7.6.5.Rest of Asia Pacific

9.8. The Middle East And Africa

9.8.1.Introduction

9.8.2.Key Region-Specific Dynamics

9.8.3.Market Size Analysis, And Y-O-Y Growth Analysis (%), By Product

9.8.4.Market Size Analysis, And Y-O-Y Growth Analysis (%), By Application

9.8.5.Market Size Analysis, And Y-O-Y Growth Analysis (%), By End User

10. Global Orthobiologics Market – Competitive Landscape

10.1. Competitive scenario

10.2. Competitor strategy analysis

10.3. Comparative type portfolio analysis

10.4. Market positioning/share analysis

10.5. Mergers and acquisitions analysis

11. Company Profiles

11.1. Medtronic Plc.

11.1.1. Company Overview

11.1.2. Type Portfolio And Description

11.1.3. Key Highlights

11.1.4. Financial Overview

11.2. Zimmer Biomet

11.3. Stryker Corporation

11.4. DePuy Synthes Inc.

11.5. Sanofi

11.6. Seaspine Holdings Corporation

11.7. RTI Surgicals 

11.8. Arthrex Inc. 

11.9. Integra LifeSciences Holdings

11.10. Globus Medical Inc.

12. Global Orthobiologics Market – Premium Insights

13. Global Orthobiologics Market – DataM

13.1. Appendix

13.2.About us and services

LIST OF TABLES

1. Global Orthobiologics Market Value, By Product, 2018,2022 & 2026 ($ Million)

2. Global Orthobiologics Market Value, By Application, 2018,2022 & 2026 ($ Million)

3. Global Orthobiologics Market Value, By End User, 2018,2022 & 2026 ($ Million)

4. Global Orthobiologics Market Value, By Region, 2018,2022 & 2026 ($ Million)

5. Global Orthobiologics Market Value, By Product, 2018,2022 & 2026 ($ Million)

6. Global Orthobiologics Market Value, By Product, 2017-2026 ($ Million)

7. Global Orthobiologics Market Value, By Application, 2018,2022 & 2026 ($ Million)

8. Global Orthobiologics Market Value, By Application, 2017-2026 ($ Million)

9. Global Orthobiologics Market Value, By End User, 2018,2022 & 2026 ($ Million)

10. Global Orthobiologics Market Value, By End User, 2017-2026 ($ Million)

11. Global Orthobiologics Market Value, By Region, 2018,2022 & 2026 ($ Million)

12. Global Orthobiologics Market Value, By Region, 2017-2026 ($ Million)

13. North America Orthobiologics Market Value, By Product, 2017-2026 ($ Million)

14. North America Orthobiologics Market Value, By Application, 2017-2026 ($ Million)

15. North America Orthobiologics Market Value, By End User, 2017-2026 ($ Million)

16. North America Orthobiologics Market Value, By Country, 2017-2026 ($ Million)

17. South America Orthobiologics Market Value, By Product, 2017-2026 ($ Million)

18. South America Orthobiologics Market Value, By Application, 2017-2026 ($ Million)

19. South America Orthobiologics Market Value, By End User, 2017-2026 ($ Million)

20. South America Orthobiologics Market Value, By Country, 2017-2026 ($ Million)

21. Europe Orthobiologics Market Value, By Product, 2017-2026 ($ Million)

22. Europe Orthobiologics Market Value, By Application, 2017-2026 ($ Million)

23. Europe Orthobiologics Market Value, By End User, 2017-2026 ($ Million)

24. Europe Orthobiologics Market Value, By Country, 2017-2026 ($ Million)

25. Asia-Pacific Orthobiologics Market Value, By Product, 2017-2026 ($ Million)

26. Asia-Pacific Orthobiologics Market Value, By Application, 2017-2026 ($ Million)

27. Asia-Pacific Orthobiologics Market Value, By End User, 2017-2026 ($ Million)

28. Asia-Pacific Orthobiologics Market Value, By Country, 2017-2026 ($ Million)

29. Middle East & Africa Orthobiologics Market Value, By Product, 2017-2026 ($ Million)

30. Middle East & Africa Orthobiologics Market Value, By Application, 2017-2026 ($ Million)

31. Middle East & Africa Orthobiologics Market Value, By End User, 2017-2026 ($ Million)

32. Medtronic Plc.: Overview

33. Medtronic Plc.: Product Portfolio

34. Medtronic Plc.: Key Developments

35. Zimmer Biomet: Overview

36. Zimmer Biomet: Product Portfolio

37. Zimmer Biomet: Key Developments

38. Stryker Corporation: Overview

39. Stryker Corporation: Product Portfolio

40. Stryker Corporation: Key Developments

41. DePuy Synthes Inc.: Overview

42. DePuy Synthes Inc.: Product Portfolio

43. DePuy Synthes Inc.: Key Developments

44. Sanofi: Overview

45. Sanofi: Product Portfolio

46. Sanofi: Key Developments

47. Seaspine Holdings Corporation: Overview

48. Seaspine Holdings Corporation: Product Portfolio

49. Seaspine Holdings Corporation: Key Developments

50. RTI Surgicals: Overview

51. RTI Surgicals: Product Portfolio

52. RTI Surgicals: Key Developments

53. Arthrex Inc.: Overview

54. Arthrex Inc.: Product Portfolio

55. Arthrex Inc.: Key Developments

56. Integra LifeSciences Holdings: Overview

57. Integra LifeSciences Holdings: Product Portfolio

58. Integra LifeSciences Holdings: Key Developments

59. Globus Medical Inc.: Overview

60. Globus Medical Inc.: Product Portfolio

61. Globus Medical Inc.: Key Developments


LIST OF FIGURES

1. Global Orthobiologics Market Share, By Product, 2018 & 2026 (%)

2. Global Orthobiologics Market Share, By Application, 2018 & 2026 (%)

3. Global Orthobiologics Market Share, By End User, 2018 & 2026 (%)

4. Global Orthobiologics Market Share, By Region, 2018 & 2026 (%)

5. Global Orthobiologics Market Value, 2017-2026 ($ Million)

6. Global Orthobiologics Market Y-o-Y Growth, By Product, 2018-2026 (%)

7. Demineralized Bone Matrix: Global Orthobiologics Market Value, 2017-2026 ($ Million)

8. Synthetic Bone Substitutes: Global Orthobiologics Market Value, 2017-2026 ($ Million)

9. Viscosupplements: Global Orthobiologics Market Value, 2017-2026 ($ Million)

10. Allografts: Global Orthobiologics Market Value, 2017-2026 ($ Million)

11. Stem cell: Global Orthobiologics Market Value, 2017-2026 ($ Million)

12. Others: Global Orthobiologics Market Value, 2017-2026 ($ Million)

13. Global Orthobiologics Market Y-o-Y Growth, By Application, 2018-2026 (%)

14. Spinal Fusion: Global Orthobiologics Market Value, 2017-2026 ($ Million)

15. Fracture Recovery: Global Orthobiologics Market Value, 2017-2026 ($ Million)

16. Soft Tissue Injuries: Global Orthobiologics Market Value, 2017-2026 ($ Million)

17. Maxillofacial & Dental Applications: Global Orthobiologics Market Value, 2017-2026 ($ Million)

18. Global Orthobiologics Market Y-o-Y Growth, By End User, 2018-2026 (%)

19. Hospitals: Global Orthobiologics Market Value, 2017-2026 ($ Million)

20. Orthopedic Clinics: Global Orthobiologics Market Value, 2017-2026 ($ Million)

21. Dental Clinics: Global Orthobiologics Market Value, 2017-2026 ($ Million)

22. Others: Global Orthobiologics Market Value, 2017-2026 ($ Million)

23. Global Orthobiologics Market Y-o-Y Growth, By Region, 2018-2026 (%)

24. North America Orthobiologics Market Value, 2017-2026 ($ Million)

25. North America Orthobiologics Market Share, By Product, 2018 & 2026 (%)

26. North America Orthobiologics Market Share, By Application, 2018 & 2026 (%)

27. North America Orthobiologics Market Share, By End User, 2018 & 2026 (%)

28. North America Orthobiologics Market Share, By Country, 2018 & 2026 (%)

29. South America Orthobiologics Market Value, 2017-2026 ($ Million)

30. South America Orthobiologics Market Share, By Product, 2018 & 2026 (%)

31. South America Orthobiologics Market Share, By Application, 2018 & 2026 (%)

32. South America Orthobiologics Market Share, By End User, 2018 & 2026 (%)

33. South America Orthobiologics Market Share, By Country, 2018 & 2026 (%)

34. Europe Orthobiologics Market Value, 2017-2026 ($ Million)

35. Europe Orthobiologics Market Share, By Product, 2018 & 2026 (%)

36. Europe Orthobiologics Market Share, By Application, 2018 & 2026 (%)

37. Europe Orthobiologics Market Share, By End User, 2018 & 2026 (%)

38. Europe Orthobiologics Market Share, By Country, 2018 & 2026 (%)

39. Asia-Pacific Orthobiologics Market Value, 2017-2026 ($ Million)

40. Asia-Pacific Orthobiologics Market Share, By Product, 2018 & 2026 (%)

41. Asia-Pacific Orthobiologics Market Share, By Application, 2018 & 2026 (%)

42. Asia-Pacific Orthobiologics Market Share, By End User, 2018 & 2026 (%)

43. Asia-Pacific Orthobiologics Market Share, By Country, 2018 & 2026 (%)

44. Middle East & Africa Orthobiologics Market Value, 2017-2026 ($ Million)

45. Middle East & Africa Orthobiologics Market Share, By Product, 2018 & 2026 (%)

46. Middle East & Africa Orthobiologics Market Share, By Application, 2018 & 2026 (%)

47. Middle East & Africa Orthobiologics Market Share, By End User, 2018 & 2026 (%)

48. Medtronic Plc.: Financials

49. Zimmer Biomet: Financials

50. Stryker Corporation: Financials

51. DePuy Synthes Inc.: Financials

52. Sanofi: Financials

53. Seaspine Holdings Corporation: Financials

54. RTI Surgicals: Financials

55. Arthrex Inc.: Financials

56. Integra LifeSciences Holdings: Financials

Globus Medical Inc.: Financials

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