Electroporation Instruments and Consumables Market

SKU: DMBT4021 | Last Updated On: Dec 01 2021 | No. of Pages: 180 | Available Formats

> Global Electroporation Instruments and Consumables Market Expected to reach a high CAGR By 2028: DataM Intelligence

Global Electroporation Instruments and Consumables Market is segmented By Product (Instruments, Consumables), By Application (Protein Production, Bio-Medical Research, Therapeutic Delivery), By Region (North America, Europe, South America, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2021-2028

 

Market Overview

The global electroporation instruments and consumablesmarket size was worth US$ YY million in 2020 and is estimated to reach US$ YY million by 2028, growing at a CAGR of YY % during the forecast period (2021-2028).

Electroporation instruments use a molecular biology technology based on electrical conductivity to generate permeability in the cell membrane through which molecule of interest can pass through it passively. The consumables are essential goods which are used along with the electroporation system and to be changed in the regular basis.

Source: DataM Intelligence Analysis (2021)

Market Dynamics

The global electroporation instruments and consumablesmarket growth is driven by theincreasing research and development funding by public and private bodies. In addition, with the increase in the technological advancements in the fields of nanotechnology, biotechnology, and pharmacology, increases its penetration rates.

Progress in gene editing techniquesis expected to drive the growth in the forecast period

The advancements in gene-editing technologies, including regularly- interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins or transcription activator-like effector nucleases (TALENs), have enabled the researchers to curate targeted sequence-specific changes across the DNA– a factor that is expected to rise the adoption of electroporation instruments.As the advancements in gene-editing techniques occur at a steady pace, the prospects of this market continue to look at a bright future.

Moreover, as applications of gene editing techniques continue to increase research and development, the adoption of electroporation instruments is likely to witness considerable growth. In addition, significant advancements in the electroporation instruments and electrodes coupled with the increasing compatibility with cutting-edge gene-editing technology are likely to play a key role in the overall development of the global electroporation instruments and consumables market.

For instance, in June 2018, first genome editing method for R. eutropha using an electroporation-based CRISPR-Cas9 approach was presented inresearch. This method significantly increased the efficiency and decreased time to manipulate this facultative chemolithoautotrophic microbe. The novel technique will facilitate more advanced researches and applications of R. eutropha for PHA production and CO2 conversion.

Non-specific transport and other complicationsis expected to drive the growth in the forecast period

When compared to other delivery systems, electroporation methods have few drawbacks. In some situations, non-specific material transport can cause an ion imbalance, which can lead to cellular dysfunction and death. Irreversible electroporation, which is usually regarded as an unusual method of cell death, could result in the loss of cell homeostasis.Electroporation method causes complication and skin edema, as compared to other physical methods. In other chemical methods, instruments are not required, which are highly preferred by some researchers. However, in some instances, electroporation effectiveness is widely influenced by other factors such as cell or tissue type and DNA formulation.

Moreover, the major drawback of electroporation is substantial cell death caused by high voltage pulses and only partially successful membrane repair, requiring the use of greater quantities of cells compared to chemical transfection methods.Several laboratories have reported the harmful effects of electroporation on cells due to local pH changes, the emergence of toxic electrode products, temperature increases, and the heterogeneity of the electric field operating on cells in the cuvettes used for electroporation.InvitrogenNeon Transfection System by Thermo Fisher, overcomes high cell mortality by distributing the electrical pulse equally among the cells and maintaining a stable pH throughout the electroporation chamber. However, optimization of pulse and field strength parameters is still required to balance the electroporation efficiency and cell viability.

COVID-19 Impact Analysis

The impact of the COVID-19 pandemic on the global electroporation instruments & consumables market is expected to remain moderate in 2020, as research and development activities are likely to remain unaffected.

Furthermore, increasing adoption of the gene editing technology across the healthcare sector worldwide is likely to continue in 2020 due to which, the electroporation instruments & consumables market is projected to witness steady growth.As precision medicines are playing an imperative role in assisting researchers and scientists to evaluate the novel coronavirus, the demand for electroporation instruments is likely to grow.In addition, CRISPR-based diagnostics are increasingly being used to accurately diagnose a range of medical diseases, including the novel COVID-19 infection another factor that is expected to propel the growth of the market for electroporation instruments during the pandemic.Electroporation has been shown to have a significant impact on vaccine immunogenicity and efficacy. This is because it has the potential to increase antigen delivery as much as a 1000-fold over naked DNA delivery technologies alone.This increased delivery translates to an improved immune response magnitude as well as improved response rates relative to DNA delivery by direct injection alone.Electroporation is accomplished through a sterile, disposable needle array attached to an applicator. The DNA plasmid of interest is delivered separately via intradermal or intramuscular needle injection to an area marked by the electrodes immediately prior to the electroporation treatment. The electroporation treatment is achieved by introducing an electrical pulse/s of defined magnitude and length to the cells of interest.

Segment Analysis

Thetotal electroporation systemsegmentis expected to hold the largest share in this market segment

The total electroporation system is the complete electroporation system for transfection of both eukaryotic and prokaryotic cells. The system features modifiable delivery parameters including time constant, actual voltage applied, pulse interval, and pulse time, depending on the waveform chosen. Total Electroporation System are flexible systems allowing both square wave and exponential decay wave electroporation in a single unit. These waveform combinations enable researchers to easily and efficiently electroporation eukaryotic and prokaryotic cells in cuvettes or plates with one easy-to-use setup. With a wide range of pulsing parameters, advanced safety features as well as dozens of preset protocols, total electroporation system can be used in any lab requiring efficient cell transfection or transformation without the use of costly reagents.These systems incorporate remote operation functionality via footswitch or PC and internal log storage of experiment data for easy optimization, quality control requirements and troubleshooting.It allows researchers to select which type of waveform they would like to use to transfect eukaryotic cells or transform prokaryotic cells. Typically, eukaryotic cells respond best to square wave pulses while prokaryotic cell respond well to exponential decay wave pulses. Combining these two waveforms gives researchers total flexibility to achieve the highest efficiency for their application.

Source: DataM Intelligence Analysis (2021)

Geographical Analysis

North America region holds the largest market share of global electroporation instruments and consumables market

The North American region dominated the global electroporation instruments & consumables market, followed by Europe. The rise in prevalence of cancer and autoimmune diseases in North America fueled the market. The advanced healthcare infrastructure coupled with rapid advancements in technology is expected to play an imperative role in boosting the growth of these region electroporation instruments & consumables market. Moreover, the approval rate of electroporation instruments across Europe and North America is comparatively higher than that across the Asia Pacific.

As per the World Health Organization (WHO), Cancer is the second-most leading cause of death worldwide, accounting for over 18.1 million cases were diagnosed in 2018. In 2020, around 19 Mn new cancer cases were diagnosed across the world as per the WHO. Likewise, the American Cancer Society reported that 89,500 cases were diagnosed in the U.S. in 2020. Additionally, according to International Agency for Research on Cancer (IARC) estimates, by 2040, global cancer cases are expected to grow to 27.5 million new cancer cases worldwide. This number has led to an increase in the adoption of various electroporation methods.

Source: DataM Intelligence Analysis (2021)

Competitive Landscape

The global electroporation instruments and consumables market is highly competitive with presence of local as well as global companies. Some of the key players which are contributing to the growth of the market includeThermo Fisher Scientific Inc, Bio-Rad Laboratories, BEX Co. Ltd, Celetrix LLC, Merck KGaA, Eppendorf AG, Harvard Bioscience Inc. (BTX), MaxCyte Inc, Lonza Group, Mirus Bio LLC.The major players are adopting several growth strategies such as product launches, acquisitions, and collaborations, which are contributing to the growth of the wound care management devices globally. For instance,In August 2021, MaxCyte signed clinical and commercial license with Sana Biotechnology. The agreement represents MaxCyte's 14th strategic platform license (SPL) Sana will use MaxCyte's Flow Electroporation technology and ExPERT platform in conjunction with the development of its hypoimmune cell therapy programs.

Key Companies to Watch

Thermo Fisher Scientific

Overview:Thermo Fisher Scientific is global manufacturer and provider of scientific instrumentation, reagents and consumables, and software and services to healthcare, life science, and other laboratories in academia, government, and industry.The company’s Lipofectamine reagent–specific protocols have been optimized for efficiency, viability, and reproducibility across a broad range of cell types. The company delivers a combination of innovative technologies, purchasing convenience and pharmaceutical services through various industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services and Patheon.

Product Portfolio: It includes products like Neon Transfection System, MegaX DH10B T1R Electrocomp Cells, TOP10 Electrocomp Kit, One Shot TOP10 Electrocomp E. coli Invitrogen.

Neon Transfection System-Next-generation electroporation device—highly efficient transfection of primary cells, stem cells, and difficult-to-transfect cells. It utilizes a proprietary biologically compatible pipette tip chamber to generate a more uniform electric field for a significant increase in transfection efficiency and cell viability.

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The global electroporation instruments and consumables market report would provide an access to an approx. 40+ market data table, 45+ figures and 180 pages. 

Target Audience

  • Service Providers/ Buyers
  • Industry Investors/Investment Bankers
  • Education & Research Institutes
  • Research Professionals
  • Emerging Companies
  • Manufacturers

Market Segmentation

Global Electroporation Instruments and Consumables Market– By Product

  • Instruments
    • Total Electroporation System
    • Eukaryotic Electroporation System
    • Microbial Electroporation System
  •  Consumables 
    • Electroporation Cuvettes
    • Electroporation Buffer
    • Electroporation Plates
    •   Others (Cables & Adapters, etc.)

Global Electroporation Instruments and Consumables Market – By Application

  • Protein Production
  • Bio-Medical Research
    • Transgenic models
    • Cancer Research
    • Gene and Protein Expression Studies
    • Cell-based Microarrays for Drug Discovery and Development
  • Therapeutic Delivery
    • Biotherapeutics
    • Electro-chemotherapy and Electro-immunotherapy

Global Electroporation Instruments and Consumables Market - By Region

  • North America
  • Europe
  • Asia-Pacific
  • Middle East & Africa
  • South America

Table of Contents

  1. Global Electroporation Instruments and Consumables Methodology and Scope

    1. Research Methodology
    2. Research Objective and Scope of the Report
  2. Global Electroporation Instruments and Consumables Market – Market Definition and Overview

  3. Global Electroporation Instruments and Consumables Market – Executive Summary

    1. Market Snippet by Product
    2. Market Snippet by Application
    3. Market Snippet by Region
  4. Global Electroporation Instruments and Consumables Market – Market Dynamics

    1. Market Impacting Factors
      1. Drivers
        1. Progress in gene editing techniques
      2. Restraints:
        1. Non-specific transport and other complications
      3. Opportunity
      4. Impact Analysis
  5. Global Electroporation Instruments and Consumables Market – Industry Analysis

    1. Porter's Five Forces Analysis
    2. PEST Analysis
    3. Supply Chain Analysis
    4. Pricing Analysis
    5. Regulatory Analysis
    6. Unmet Needs
  6. Global Electroporation Instruments and Consumables Market – COVID-19 Analysis

    1. Analysis of Covid-19 on the Market
      1. Before COVID-19 Market Scenario
      2. Present COVID-19 Market Scenario
      3. After COVID-19 or Future Scenario
    2. Pricing Dynamics Amid Covid-19
    3. Demand-Supply Spectrum
    4. Government Initiatives Related to the Market During Pandemic
    5. Manufacturers Strategic Initiatives
    6. Conclusion 
  7. Global Electroporation Instruments and Consumables Market – By Application

    1. Introduction
      1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
      2. Market Attractiveness Index, By Application
    2. Bio-Medical Research*
      1. Introduction
      2. Market Size Analysis, US$ Million, 2018-2028 and Y-o-Y Growth Analysis (%), 2020-2028
      3. Transgenic models
      4. Cancer Research
      5. Gene and Protein Expression Studies
      6. Cell-based Microarrays for Drug Discovery and Development
    3. Protein Production
    4. Therapeutic Delivery
      1. Biotherapeutics
      2. Electro-chemotherapy and Electro-immunotherapy
  8. Global Electroporation Instruments and Consumables Market – By Product

    1. Introduction
      1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
      2. Market Attractiveness Index, By Product
    2. Instruments*
      1. Introduction
      2. Market Size Analysis, US$ Million, 2018-2028 and Y-o-Y Growth Analysis (%), 2020-2028
      3. Total Electroporation System
      4. Eukaryotic Electroporation System
      5. Microbial Electroporation System
    3. Consumables 
      1. Electroporation Cuvettes
      2. Electroporation Buffer
      3. Electroporation Plates
    4.   Others (Cables & Adapters, etc.)
  9. Global Electroporation Instruments and Consumables Market – By Region

    1. Introduction
      1. Market Size Analysis, US$ Million, 2018-2028 and Y-o-Y Growth Analysis (%), 2020-2028, By Region
      2. Market Attractiveness Index, By Region
    2. North America
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), ByApplication
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. U.S.
        2. Canada
        3. Mexico
    3. Europe
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), ByApplication
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. Germany
        2. U.K.
        3. France
        4. Italy
        5. Spain
        6. Rest of Europe
    4. South America
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), ByApplication
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. Brazil
        2. Argentina
        3. Rest of South America
    5. Asia Pacific
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), ByApplication
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. China
        2. India
        3. Japan
        4. Australia
        5. Rest of Asia Pacific
    6. Middle East and Africa
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), ByApplication
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
  10. Global Electroporation Instruments and Consumables Market – Competitive Landscape

    1. Competitive Scenario
    2. Key Developments and Strategies
    3. Company Share Analysis
    4. Product Benchmarking
    5. Key Companies to Watch
    6. Company with disruptive technology
  11. Global Electroporation Instruments and Consumables Market- Company Profiles

    1. Thermo Fisher Scientific Inc*
      1. Company Overview
      2. Product Portfolio and Description
      3. Key Highlights
      4. Financial Overview
    2. Bio-Rad Laboratories
    3. BEX Co. Ltd
    4. Celetrix LLC
    5. Merck KGaA
    6. Eppendorf AG
    7. Harvard Bioscience Inc. (BTX)
    8. MaxCyte Inc
    9. Lonza Group
    10. Mirus Bio LLC (*LIST NOT EXHAUSTIVE)
  12. Global Electroporation Instruments and Consumables Market – DataM

    1. Appendix
    2. About Us and Services
    3. Contact Us

List of Tables & Figures

List of Tables

Table 1Global Electroporation Instruments and Consumables Market Value, By Product, 2020, 2024 & 2028 ($ Million)

Table 2Global Electroporation Instruments and Consumables Market Value, By Application, 2020, 2024 & 2028 ($ Million)

Table 3Global Electroporation Instruments and Consumables Market Value, By Region, 2020, 2024 & 2028 ($ Million)

Table 4Global Electroporation Instruments and Consumables Market Value, By Product, 2020, 2024 & 2028 ($ Million)

Table 5Global Electroporation Instruments and Consumables Market Value, By Product, 2019-2028 ($ Million)

Table 6Global Electroporation Instruments and Consumables Market Value, By Application, 2020, 2024 & 2028 ($ Million)

Table 7Global Electroporation Instruments and Consumables Market Value, By Application, 2019-2028 ($ Million)

Table 8Global Electroporation Instruments and Consumables Market Value, By Region, 2020, 2024 & 2028 ($ Million)

Table 9Global Electroporation Instruments and Consumables Market Value, By Region, 2019-2028 ($ Million)

Table 10North America Electroporation Instruments and Consumables Market Value, By Product, 2019-2028 ($ Million)

Table 11North America Electroporation Instruments and Consumables Market Value, By Application, 2019-2028 ($ Million)

Table 12North America Electroporation Instruments and Consumables Market Value, By Country, 2019-2028 ($ Million)

Table 13South America Electroporation Instruments and Consumables Market Value, By Product, 2019-2028 ($ Million)

Table 14South America Electroporation Instruments and Consumables Market Value, By Application, 2019-2028 ($ Million)

Table 15South America Electroporation Instruments and Consumables Market Value, By Country, 2019-2028 ($ Million)

Table 16Europe Electroporation Instruments and Consumables Market Value, By Product, 2019-2028 ($ Million)

Table 17Europe Electroporation Instruments and Consumables Market Value, By Application, 2019-2028 ($ Million)

Table 18Europe Electroporation Instruments and Consumables Market Value, By Country, 2019-2028 ($ Million)

Table 19Asia-Pacific Electroporation Instruments and Consumables Market Value, By Product, 2019-2028 ($ Million)

Table 20Asia-Pacific Electroporation Instruments and Consumables Market Value, By Application, 2019-2028 ($ Million)

Table 21Asia-Pacific Electroporation Instruments and Consumables Market Value, By Country, 2019-2028 ($ Million)

Table 22Middle East & Africa Electroporation Instruments and Consumables Market Value, By Product, 2019-2028 ($ Million)

Table 23Middle East & Africa Electroporation Instruments and Consumables Market Value, By Application, 2019-2028 ($ Million)

Table 24Bio-Rad Laboratories: Overview

Table 25Bio-Rad Laboratories: Product Portfolio

Table 26Bio-Rad Laboratories: Key Developments

Table 27BEX Co. Ltd: Overview

Table 28BEX Co. Ltd: Product Portfolio

Table 29BEX Co. Ltd: Key Developments

Table 30Celetrix LLC: Overview

Table 31Celetrix LLC: Product Portfolio

Table 32Celetrix LLC: Key Developments

Table 33Merck KGaA: Overview

Table 34Merck KGaA: Product Portfolio

Table 35Merck KGaA: Key Developments

Table 36Eppendorf AG: Overview

Table 37Eppendorf AG: Product Portfolio

Table 38Eppendorf AG: Key Developments

Table 39Harvard Bioscience Inc. (BTX): Overview

Table 40Harvard Bioscience Inc. (BTX): Product Portfolio

Table 41Harvard Bioscience Inc. (BTX): Key Developments

Table 42MaxCyte Inc: Overview

Table 43MaxCyte Inc: Product Portfolio

Table 44MaxCyte Inc: Key Developments

Table 45Lonza Group: Overview

Table 46Lonza Group: Product Portfolio

Table 47Lonza Group: Key Developments

Table 48Mirus Bio LLC: Overview

Table 49Mirus Bio LLC: Product Portfolio

Table 50Mirus Bio LLC: Key Developments

Table 51Thermo Fisher Scientific Inc: Overview

Table 52Thermo Fisher Scientific Inc: Product Portfolio

Table 53Thermo Fisher Scientific Inc: Key Developments

List of Figures

Figure 1Global Electroporation Instruments and Consumables Market Share, By Product, 2020 & 2028 (%)

Figure 2Global Electroporation Instruments and Consumables Market Share, By Application, 2020 & 2028 (%)

Figure 3Global Electroporation Instruments and Consumables Market Share, By Region, 2020 & 2028 (%)

Figure 4Global Electroporation Instruments and Consumables Market Value, 2019-2028 ($ Million)

Figure 5Global Electroporation Instruments and Consumables Market Y-o-Y Growth, By Product, 2020-2028 (%)

Figure 6Instruments: Global Electroporation Instruments and Consumables Market Value, 2019-2028 ($ Million)

Figure 7Consumables: Global Electroporation Instruments and Consumables Market Value, 2019-2028 ($ Million)

Figure 8Global Electroporation Instruments and Consumables Market Y-o-Y Growth, By Application, 2020-2028 (%)

Figure 9Protein Production: Global Electroporation Instruments and Consumables Market Value, 2019-2028 ($ Million)

Figure 10Bio-Medical Research: Global Electroporation Instruments and Consumables Market Value, 2019-2028 ($ Million)

Figure 11Therapeutic Delivery: Global Electroporation Instruments and Consumables Market Value, 2019-2028 ($ Million)

Figure 12Global Electroporation Instruments and Consumables Market Y-o-Y Growth, By Region, 2020-2028 (%)

Figure 13North America Electroporation Instruments and Consumables Market Value, 2019-2028 ($ Million)

Figure 14North America Electroporation Instruments and Consumables Market Share, By Product, 2020 & 2028 (%)

Figure 15North America Electroporation Instruments and Consumables Market Share, By Application, 2020 & 2028 (%)

Figure 16North America Electroporation Instruments and Consumables Market Share, By Country, 2020 & 2028 (%)

Figure 17South America Electroporation Instruments and Consumables Market Value, 2019-2028 ($ Million)

Figure 18South America Electroporation Instruments and Consumables Market Share, By Product, 2020 & 2028 (%)

Figure 19South America Electroporation Instruments and Consumables Market Share, By Application, 2020 & 2028 (%)

Figure 20South America Electroporation Instruments and Consumables Market Share, By Country, 2020 & 2028 (%)

Figure 21Europe Electroporation Instruments and Consumables Market Value, 2019-2028 ($ Million)

Figure 22Europe Electroporation Instruments and Consumables Market Share, By Product, 2020 & 2028 (%)

Figure 23Europe Electroporation Instruments and Consumables Market Share, By Application, 2020 & 2028 (%)

Figure 24Europe Electroporation Instruments and Consumables Market Share, By Country, 2020 & 2028 (%)

Figure 25Asia-Pacific Electroporation Instruments and Consumables Market Value, 2019-2028 ($ Million)

Figure 26Asia-Pacific Electroporation Instruments and Consumables Market Share, By Product, 2020 & 2028 (%)

Figure 27Asia-Pacific Electroporation Instruments and Consumables Market Share, By Application, 2020 & 2028 (%)

Figure 28Asia-Pacific Electroporation Instruments and Consumables Market Share, By Country, 2020 & 2028 (%)

Figure 29Middle East & Africa Electroporation Instruments and Consumables Market Value, 2019-2028 ($ Million)

Figure 30Middle East & Africa Electroporation Instruments and Consumables Market Share, By Product, 2020 & 2028 (%)

Figure 31Middle East & Africa Electroporation Instruments and Consumables Market Share, By Application, 2020 & 2028 (%)

Figure 32Bio-Rad Laboratories: Financials

Figure 33BEX Co. Ltd: Financials

Figure 34Celetrix LLC: Financials

Figure 35Merck KGaA: Financials

Figure 36Eppendorf AG: Financials

Figure 37Harvard Bioscience Inc. (BTX): Financials

Figure 38MaxCyte Inc: Financials

Figure 39Lonza Group: Financials

Figure 40Mirus Bio LLC: Financials

Figure 41Thermo Fisher Scientific Inc: Financials

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