Xerostomia Therapeutics Market

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> Global Xerostomia Therapeutics Market Expected to reach a high CAGR of 3.8% By 2028: DataM Intelligence

Global Xerostomia Therapeutics Market is segmented By Type (OTC, Prescription), By Product Type (Salivary Stimulants, Salivary Substitutes, Dentifrices, Artificial Saliva, Salivary Pen), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2021-2028

 

Market Overview

The Global "Xerostomia therapeutics Market" is expected to grow at a CAGR of 3.8% during the forecast period (2021-2028).

Xerostomia is defined as dry mouth resulting from reduced or absent saliva flow. Xerostomia is not a disease but is symptoms of toxicity from chemotherapy, head and neck radiotherapy, adverse effects of medications, autoimmune disease, or other conditions such as uncontrolled diabetes, infections, and hormonal changes. Xerostomia occurs commonly in those with Sjögren disease or who are receiving radiation therapy for head and neck cancer. Xerostomia is a common complaint found often among older adults, affecting approximately 20% of the elderly. Reduced salivary flow can cause difficulties in tasting, chewing, swallowing, and speaking; it can also increase the chance of developing dental decay, demineralization of teeth, tooth sensitivity, and oral infections.

Market Overview

**Source: DataM Intelligence Analysis (2019)

Market Dynamics

The xerostomia therapeutics market growth is driven by several factors, such as an increase in chemotherapy, growing awareness and rising prevalence of xerostomia and associated diseases.

Growing occurrence of xerostomia and related diseases such as hypertension, Parkinson’s disorder, Sjogren’s syndrome and diabetes have a positive impact on market growth. Diabetes is one of the major cause that causes dry mouth; there is less moisture for other things when the body is using fluids to make urine that happens in diabetes. Diabetes hence leads to dehydrated body, and mouth that feels dry. Xerostomia can exacerbate the side effects of diabetes, which will then lead to an increase in glucose levels, wreaking havoc on the body. Having xerostomia, especially as a diabetes patient, can lead to rampant tooth decay, which means blood sugar increases as the body tries to fight infection. A dry mouth can also lead to loss of sleep and an altered sense of taste, a condition that presents with a metallic or sour taste in the mouth. Xerostomia is a common symptom in the elderly population. Studies have suggested that the underlying cause of approximately 40% of xerostomia in the elderly is Sjogren's syndrome. Sjogren’s syndrome is the third most common rheumatic autoimmune disorder. The population prevalence of Sjogren’s syndrome is  0.2%, with an incidence of 4 cases per 100,000 per year.  Sjogren’s is 20 times more common in females than males. In Sjogren's syndrome, it attacks the glands that make tears and saliva. This causes a dry mouth and dry eyes, hence increasing the cases of xerostomia.

With increasing cases of cancer globally, there is an increase in chemotherapy as well. Chemotherapy is used as a treatment for the majority of cancers that occurs. According to the World Health Organization (WHO), cancer is the second leading cause of death globally and is responsible for an estimated 9.6 million deaths in 2018. Globally, about one in six deaths are due to cancer. On an average around 26% of the patients who have cancer undergo chemotherapy each year, and this is increasing with increasing cases of cancer. Chemotherapy and radiation therapy cause dry mouth by damaging the salivary glands. Chemotherapy causes dry mouth by making saliva thicker. Hence, increase in chemotherapy increases prevalence of xerostomia.

Market Segmentation

By product type, the global xerostomia therapeutics market is segmented into salivary stimulants, salivary substitutes, dentifrices, artificial saliva, and salivary pen. Salivary stimulants are expected to be the largest market shareholder over the period of forecast (2020-2027). Topical products to salivary stimulant flow include a variety of over the counter sugar-free gums, mints, and candies. Salivary stimulants include the sialagogues pilocarpine hydrochloride (Salagen®) and cevimeline hydrochloride (Evoxac®). Pilocarpine and cevimeline bind to muscarinic receptors, stimulating exocrine gland activity (such as salivary and sweat glands) and increased smooth muscle tone in the gastrointestinal and urinary tracts. Common adverse effects include sweating, headache, GI discomfort, nausea, increased lacrimation, urinary frequency, and palpitations. Sialogogic drugs are substances designed to stimulate salivary secretion as they have an effect on the systemic pathway. The use of sugar-free chewing gum or tablet can increase salivary secretion and improve the sensation of dry mouth together with gustatory and masticatory stimulation. These products can additionally be fluoride, chlorhexidine, calcium phosphate, and xylitol releasers. Salivary stimulants are highly popular as they are very readily available and can be taken without any adverse effects.

Geographical Analysis

North America is dominating the xerostomia therapeutics market in 2018 and estimated to hold the largest market size over the forecast period (2020-2027), owing to an increase in cancer and xerostomia associated disorders such as Sjogren’s disorder, a highly aware population, advanced healthcare infrastructure, favourable government initiatives and growth in research and development. According to National Cancer Institute, in 2018, an estimated 1,735,350 new cases of cancer were diagnosed in the US, and 609,640 people died from the disease. These numbers are increasing with each passing year, along with the causes such as lifestyle changes, smoking and many more. US is very advanced in healthcare and population is generally aware, this leads to growing cases of chemotherapy treatment which leads to xerostomia. Similarly other diseases associated with xerostomia such as Parkinson’s and Sjogren’s syndrome are also on the rise in the region, with upwards of 4,000,000 Americans suffering from Sjögren’s, it is one of the most prevalent autoimmune diseases. Nine out of 10 patients are women. Initiatives launched by various organisations such as “5-year breakthrough goal”  by Sjogren’s Syndrome Foundation that focuses on faster diagnosis and better treatment.

**Source: DataM Intelligence Analysis (2019)

Competitive Landscape

Some of the major key players in the market are GlaxoSmithKline, Church & Dwight Co., Inc., Colgate-Palmolive Company, Acacia Pharma Group plc, Hikma Pharmaceuticals plc, Lupin Ltd., Parnell Pharmaceuticals Inc., Pendopharm, Pfizer Inc. and Sun Pharmaceutical Industries Ltd.

In the xerostomia therapeutics market, GlaxoSmithKline is going to dominate the market, owning to portfolio expansion, mergers, collaborations, and acquisitions. The key players are adopting various growth strategies such as mergers & acquisitions, partnerships, and collaborations and increasing research and development and high investment, which are contributing to the growth of the xerostomia therapeutics market globally.

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The Global Xerostomia Therapeutics Market report would provide an access to an approx., 61 market data table, 53 figures, and 200 pages.

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Table of Contents

  1. Xerostomia Therapeutics Market Methodology and Scope

    1. Research Methodology
    2. Research Objective and Scope of the Report
  2. Xerostomia Therapeutics Market – Market Definition and Overview

  3. Xerostomia Therapeutics Market – Executive Summary

    1.  Market Snippet by Type
    2. Market Snippet by Product Type
    3. Market Snippet by Distribution Channel
    4. Market Snippet by Region
    5. DataM CLO Scenario
  4. Xerostomia Therapeutics Market-Market Dynamics

    1. Market Impacting Factors
    2. Drivers
      1. Increase in chemotherapy
      2. Growing awareness
      3. Rising prevalence of xerostomia and associated diseases
    3. Restraints
      1. High cost of drugs
      2. Stringent drug approval regulations
    4. Opportunity
    5. Impact Analysis
  5. Xerostomia Therapeutics Market – Industry Analysis

    1. Porter's Five Forces Analysis
    2. Supply Chain Analysis
    3. Regulatory Analysis
    4. Epidemiology
  6. Xerostomia Therapeutics Market – By Type

    1. Introduction
      1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      2. Market Attractiveness Index, By Type
    2. OTC
      1. Introduction
      2. Market Size Analysis, and Y-o-Y Growth Analysis (%)
    3. Prescription
  7. Xerostomia Therapeutics Market – By Product Type

    1. Introduction
      1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type
      2. Market Attractiveness Index, By Product Type
    2. Salivary Stimulants
      1. Introduction
      2. Market Size Analysis, and Y-o-Y Growth Analysis (%), 2018-2028
    3.  Salivary Substitutes
    4.  Dentifrices
    5.  Artificial Saliva
    6.  Salivary Pen
  8. Xerostomia Therapeutics Market – By Distribution Channel

    1. Introduction
    2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel
    3. Market Attractiveness Index, By Distribution Channel
    4. Hospital Pharmacies
      1. Introduction
      2. Market Size Analysis, and Y-o-Y Growth Analysis (%), 2018-2028
    5. Retail Pharmacies
    6. Online Pharmacies
  9. Xerostomia Therapeutics Market – By Region

    1. Introduction
    2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Region
    3. Market Attractiveness Index, By Region
    4. North America
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel
      6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. U.S.
        2. Canada
        3. Mexico
    5. Europe
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel
      6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. Germany
        2. U.K.
        3. France
        4. Italy
        5. Spain
        6. Rest of Europe
    6. South America
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel
      6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. Brazil
        2. Argentina
        3. Rest of South America
    7. Asia-Pacific
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel
      6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. China
        2. India
        3. Japan
        4. Australia
        5. Rest of Asia Pacific
    8. The Middle East and Africa
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Distribution Channel
  10. Market – Competitive Landscape

    1. Competitive Scenario
    2. Competitor Xerostomia Therapeutics Strategy Analysis
    3. Comparative Product Portfolio Analysis
    4. Market Positioning/Share Analysis
    5. Mergers and Acquisitions Analysis
  11. Company Profiles

    1. GlaxoSmithKline plc *
      1. Company Overview
      2. Product Portfolio and Description
      3. Key Highlights
      4. Financial Overview
    2. Church & Dwight Co., Inc.
    3. Colgate-Palmolive Company
    4. Acacia Pharma Group plc
    5. Hikma Pharmaceuticals plc
    6. Lupin Ltd.
    7. Parnell Pharmaceuticals Inc.
    8. Pendopharm
    9. Pfizer Inc.
    10. Sun Pharmaceutical Industries Ltd.
    11. Synedgen Inc.
    12. Eisai Inc.
    13. Dentaid
    14. EUSA Pharma
    15. Forward Science
    16. Bausch Health
    17. Quest Products
    18. Saliwell Ltd. ("List not exhaustive")
  12. Xerostomia Therapeutics Market – Premium Insights

  13. Xerostomia Therapeutics Market – DataM

    1. Appendix
    2. About Us and Services
    3. Contact Us

List of Tables and Figures

List of Tables

Table 1 Global Xerostomia Therapeutics Market Value, By Type, 2018,2022 & 2028 ($ Million)

Table 2 Global Xerostomia Therapeutics Market Value, By Product Type, 2018,2022 & 2028 ($ Million)

Table 3 Global Xerostomia Therapeutics Market Value, By Distribution Channel, 2018,2022 & 2028 ($ Million)

Table 4 Global Xerostomia Therapeutics Market Value, By Region, 2018,2022 & 2028 ($ Million)

Table 5 Global Xerostomia Therapeutics Market Value, By Type, 2018,2022 & 2028 ($ Million)

Table 6 Global Xerostomia Therapeutics Market Value, By Type, 2017-2028 ($ Million)

Table 7 Global Xerostomia Therapeutics Market Value, By Product Type, 2018,2022 & 2028 ($ Million)

Table 8 Global Xerostomia Therapeutics Market Value, By Product Type, 2017-2028 ($ Million)

Table 9 Global Xerostomia Therapeutics Market Value, By Distribution Channel, 2018,2022 & 2028 ($ Million)

Table 10 Global Xerostomia Therapeutics Market Value, By Distribution Channel, 2017-2028 ($ Million)

Table 11 Global Xerostomia Therapeutics Market Value, By Region, 2018,2022 & 2028 ($ Million)

Table 12 Global Xerostomia Therapeutics Market Value, By Region, 2017-2028 ($ Million)

Table 13 North America Xerostomia Therapeutics Market Value, By Type, 2017-2028 ($ Million)

Table 14 North America Xerostomia Therapeutics Market Value, By Product Type, 2017-2028 ($ Million)

Table 15 North America Xerostomia Therapeutics Market Value, By Distribution Channel, 2017-2028 ($ Million)

Table 16 North America Xerostomia Therapeutics Market Value, By Country, 2017-2028 ($ Million)

Table 17 South America Xerostomia Therapeutics Market Value, By Type, 2017-2028 ($ Million)

Table 18 South America Xerostomia Therapeutics Market Value, By Product Type, 2017-2028 ($ Million)

Table 19 South America Xerostomia Therapeutics Market Value, By Distribution Channel, 2017-2028 ($ Million)

Table 20 South America Xerostomia Therapeutics Market Value, By Country, 2017-2028 ($ Million)

Table 21 Europe Xerostomia Therapeutics Market Value, By Type, 2017-2028 ($ Million)

Table 22 Europe Xerostomia Therapeutics Market Value, By Product Type, 2017-2028 ($ Million)

Table 23 Europe Xerostomia Therapeutics Market Value, By Distribution Channel, 2017-2028 ($ Million)

Table 24 Europe Xerostomia Therapeutics Market Value, By Country, 2017-2028 ($ Million)

Table 25 Asia-Pacific Xerostomia Therapeutics Market Value, By Type, 2017-2028 ($ Million)

Table 26 Asia-Pacific Xerostomia Therapeutics Market Value, By Product Type, 2017-2028 ($ Million)

Table 27 Asia-Pacific Xerostomia Therapeutics Market Value, By Distribution Channel, 2017-2028 ($ Million)

Table 28 Asia-Pacific Xerostomia Therapeutics Market Value, By Country, 2017-2028 ($ Million)

Table 29 Middle East & Africa Xerostomia Therapeutics Market Value, By Type, 2017-2028 ($ Million)

Table 30 Middle East & Africa Xerostomia Therapeutics Market Value, By Product Type, 2017-2028 ($ Million)

Table 31 Middle East & Africa Xerostomia Therapeutics Market Value, By Distribution Channel, 2017-2028 ($ Million)

Table 32 GlaxoSmithKline plc: Overview

Table 33 GlaxoSmithKline plc: Product Portfolio

Table 34 GlaxoSmithKline plc: Key Developments

Table 35 Church & Dwight Co., Inc.: Overview

Table 36 Church & Dwight Co., Inc.: Product Portfolio

Table 37 Church & Dwight Co., Inc.: Key Developments

Table 38 Colgate-Palmolive Company: Overview

Table 39 Colgate-Palmolive Company: Product Portfolio

Table 40 Colgate-Palmolive Company: Key Developments

Table 41 Acacia Pharma Group plc: Overview

Table 42 Acacia Pharma Group plc: Product Portfolio

Table 43 Acacia Pharma Group plc: Key Developments

Table 44 Hikma Pharmaceuticals plc: Overview

Table 45 Hikma Pharmaceuticals plc: Product Portfolio

Table 46 Hikma Pharmaceuticals plc: Key Developments

Table 47 Lupin Ltd.: Overview

Table 48 Lupin Ltd.: Product Portfolio

Table 49 Lupin Ltd.: Key Developments

Table 50 Parnell Pharmaceuticals Inc.: Overview

Table 51 Parnell Pharmaceuticals Inc.: Product Portfolio

Table 52 Parnell Pharmaceuticals Inc.: Key Developments

Table 53 Pendopharm: Overview

Table 54 Pendopharm: Product Portfolio

Table 55 Pendopharm: Key Developments

Table 56 Pfizer Inc.: Overview

Table 57 Pfizer Inc.: Product Portfolio

Table 58 Pfizer Inc.: Key Developments

Table 59 Sun Pharmaceutical Industries Ltd.: Overview

Table 60 Sun Pharmaceutical Industries Ltd.: Product Portfolio

Table 61 Sun Pharmaceutical Industries Ltd.: Key Developments

 

List of Figures

Figure 1 Global Xerostomia Therapeutics Market Share, By Type, 2018 & 2028 (%)

Figure 2 Global Xerostomia Therapeutics Market Share, By Product Type, 2018 & 2028 (%)

Figure 3 Global Xerostomia Therapeutics Market Share, By Distribution Channel, 2018 & 2028 (%)

Figure 4 Global Xerostomia Therapeutics Market Share, By Region, 2018 & 2028 (%)

Figure 5 Global Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 6 Global Xerostomia Therapeutics Market Y-o-Y Growth, By Type, 2018-2028 (%)

Figure 7 OTC: Global Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 8 Prescription: Global Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 9 Global Xerostomia Therapeutics Market Y-o-Y Growth, By Product Type, 2018-2028 (%)

Figure 10 Salivary Stimulants: Global Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 11 Salivary Substitutes: Global Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 12 Dentifrices: Global Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 13 Artificial Saliva: Global Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 14 Salivary Pen: Global Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 15 Global Xerostomia Therapeutics Market Y-o-Y Growth, By Distribution Channel, 2018-2028 (%)

Figure 16 Hospital Pharmacies: Global Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 17 Retail Pharmacies: Global Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 18 Online Pharmacies: Global Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 19 Global Xerostomia Therapeutics Market Y-o-Y Growth, By Region, 2018-2028 (%)

Figure 20 North America Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 21 North America Xerostomia Therapeutics Market Share, By Type, 2018 & 2028 (%)

Figure 22 North America Xerostomia Therapeutics Market Share, By Product Type, 2018 & 2028 (%)

Figure 23 North America Xerostomia Therapeutics Market Share, By Distribution Channel, 2018 & 2028 (%)

Figure 24 North America Xerostomia Therapeutics Market Share, By Country, 2018 & 2028 (%)

Figure 25 South America Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 26 South America Xerostomia Therapeutics Market Share, By Type, 2018 & 2028 (%)

Figure 27 South America Xerostomia Therapeutics Market Share, By Product Type, 2018 & 2028 (%)

Figure 28 South America Xerostomia Therapeutics Market Share, By Distribution Channel, 2018 & 2028 (%)

Figure 29 South America Xerostomia Therapeutics Market Share, By Country, 2018 & 2028 (%)

Figure 30 Europe Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 31 Europe Xerostomia Therapeutics Market Share, By Type, 2018 & 2028 (%)

Figure 32 Europe Xerostomia Therapeutics Market Share, By Product Type, 2018 & 2028 (%)

Figure 33 Europe Xerostomia Therapeutics Market Share, By Distribution Channel, 2018 & 2028 (%)

Figure 34 Europe Xerostomia Therapeutics Market Share, By Country, 2018 & 2028 (%)

Figure 35 Asia-Pacific Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 36 Asia-Pacific Xerostomia Therapeutics Market Share, By Type, 2018 & 2028 (%)

Figure 37 Asia-Pacific Xerostomia Therapeutics Market Share, By Product Type, 2018 & 2028 (%)

Figure 38 Asia-Pacific Xerostomia Therapeutics Market Share, By Distribution Channel, 2018 & 2028 (%)

Figure 39 Asia-Pacific Xerostomia Therapeutics Market Share, By Country, 2018 & 2028 (%)

Figure 40 Middle East & Africa Xerostomia Therapeutics Market Value, 2017-2028 ($ Million)

Figure 41 Middle East & Africa Xerostomia Therapeutics Market Share, By Type, 2018 & 2028 (%)

Figure 42 Middle East & Africa Xerostomia Therapeutics Market Share, By Product Type, 2018 & 2028 (%)

Figure 43 Middle East & Africa Xerostomia Therapeutics Market Share, By Distribution Channel, 2018 & 2028 (%)

Figure 44 GlaxoSmithKline plc: Financials

Figure 45 Church & Dwight Co., Inc.: Financials

Figure 46 Colgate-Palmolive Company: Financials

Figure 47 Acacia Pharma Group plc: Financials

Figure 48 Hikma Pharmaceuticals plc: Financials

Figure 49 Lupin Ltd.: Financials

Figure 50 Parnell Pharmaceuticals Inc.: Financials

Figure 51 Pendopharm: Financials

Figure 52 Pfizer Inc.: Financials

Figure 53 Sun Pharmaceutical Industries Ltd.: Financials

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