Transient Protein Expression Market Size Share and Industry Outlook to 2028

SKU: DMHC3493 | Last Updated On: Jul 08 2021 | No. of Pages: 180 | Available Formats

> Global Transient Protein Expression Market Expected to reach a high CAGR By 2028: DataM Intelligence

Global Transient Protein Expression Market is segmented By Product Type (Instruments), By Application (Genomic Research, Gene Therapy, BioProduction, Cancer Research, Drug Development), By End-user (Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, Clinical Research Organizations), By Region (North America, Europe, South America, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2021-2028

Market Overview

The global transient protein expression market size was valued US$ XX billion in 2019 and is estimated to reach US$ XX billion by 2028, growing at a CAGR of XX % during the forecast period (2021-2028).  

 Transient protein expression is a procedure that is usually used to obtain a few milligrams of protein to a hundred milligrams of protein. It is a procedure expressed quickly once the DNA encoding expression has been introduced to animal or plant cells. It is performed using an electroporation technique that allows large numbers of mutants to be screened for their abilities to network productively with receptors and effectors. 

Source: DataM Intelligence Analysis (2020)

Market Dynamics

The transient protein expression market growth is driven by the increasing due to its rapid expression time and relatively low-cost product when compared to stable transfection. Additionally, rapidly developing biopharmaceuticals and technological advancements will also drive the growth of the global transient protein expression market.

Growing adoption of precision medicines, is expected to propel the global transient protein expression market growth over the forecast period

Technological advancements have increased the adoption of molecular biology techniques for developing various therapeutic or treatment modalities. Different therapeutic modalities utilize genomic, transcriptomic information that facilitates discovering biomarkers to monitor diseases and predicts their risks. The use of personalized or precision medicines has dramatically risen due to the awareness regarding genetic variations among people. For instance, mRNA-mediated therapy is used for treating several diseases, as the therapy is characterized by decreased immunogenicity, superior translation efficacy, enhanced stability, pharmaceutical safety, and transient protein expression, since only the mRNA is modified without incorporating the host genome.

Similarly, the pharmaceutical and biotechnology industries have developed various techniques to treat cancer and neurodegenerative diseases. The transient gene expression technique has led to significant developments in the research related to neurotrauma and neurodegenerative and resulted in the introduction of precision medicines for these conditions. Technological advancements in epigenetics, genetics and proteomics support the development of therapeutics to treat various genetic and rare genetic diseases caused by single and multiple cell disorders.

The Precision Medicine Initiative launched in the US in 2015 has enhanced the use of genetic engineering, genomics, and proteomics, thereby increasing the use of transient protein expression techniques. Thus, the continuous research and development activities and rise in government initiatives to support precision medicine boost the adoption of transient protein expression techniques.

Lack of requirements of skilled researcher is likely to hamper the market growth

Transient transfections are a fast, cost-effective solution but require skilled cell culture scientists, making the workforce a limiting factor in a setting where numerous samples are processed in parallel may restrict the market growth.

Industry Analysis

PEST Analysis:

Source: DataM Intelligence Analysis (2020)

Supply Chain Analysis

Source: DataM Intelligence Analysis (2020)

COVID-19 Impact Analysis

The COVID–19 pandemic has resulted in a rise in the use of transient protein expression in vaccine development. Various researchers have started studying the novel coronavirus extensively, with the use of transient protein expression. For instance, in March–April 2020, Absolute Antibody (UK) increased the production of multigram quantities of multiple anti-SARS-CoV-2 spike proteins to develop neutralizing antibodies. Similarly, the transient protein expression was widely used to produce a positive control protein in developing in-vitro diagnostics kits.

Segment Analysis

The instruments segment is expected to hold largest share in this market segment

The instruments segment held the largest market share. This segment is also expected to dominate the market as they reduce human input, enabling continuous cell maintenance and protein production. Moreover, the same segment is anticipated to grow at the fastest rate during the forecast period. For instance, the CompacT SelecT cell culture robot is designed to allow the large-scale expression of multiple protein constructs in a transient format.

The genomic research segment is expected to hold largest share in this market segment

This segment is also expected to dominate the market as it increases DNA sequencing performance. Moreover, transient protein expression has helped in studying all the genes of a person (the genome), including their interactions with each other and the environment.

The pharmaceutical and biotechnology companies’ segment is expected to hold largest share in this market segment

This segment is also expected to dominate the market during the forecast period as pharmaceutical and biotechnology firms increase their spending on research and R&D activities. Moreover, transient protein expression has helped the recent improvements in existing technologies, and it is moving toward the industrial production of plant-based vaccines, antibodies, and biopharmaceuticals. For instance, Jan 2020: Ambrx and Sino Biopharma Announced Collaboration to Develop Two Next-Generation Biologics to develop two products enabled by Ambrx's unique non-natural amino acid incorporation technology platforms. The collaboration combines Ambrx's clinically validated ReCODE and EuCODE platforms with Sino Biopharma's strong resources and commitment to bring next-generation biologic drugs to the market.

Source: DataM Intelligence Analysis (2020)

Geographical Analysis

North America region holds the largest market share of global transient protein expression market

North America dominated the transient protein expression market due to established research infrastructure and rising interest in research activities. Both U.S and Canada have shown high growth in the transient protein expression market due to well-established infrastructure and government-supported funding policies. Europe holds the second position due to the rising adoption of technology in academic research centers and both research laboratories. In terms of growth, Asia Pacific is anticipated to be the fastest-growing transient protein expression market over the forecast period due to increasing academic research and government policies and funding for research and development in these regions.

Source: DataM Intelligence Analysis (2020)

Competitive Landscape

The global transient protein expression market is highly competitive with presence of global companies.  Some of the key players which are contributing to the growth of the market include Thermo Fisher Scientific, Promega Corporation, Merck KGaA, Takara Bio Inc, Qiagen, Sigma-Aldrich, Bio-Rad Laboratories, Inc., Sino Biological Inc, Genscript Biotech Corporation, and Agilent Technologies Inc, Sino Biopharma. The major players are adopting several growth strategies such as product launches, acquisitions, and collaborations, which are contributing to the growth of the market globally. For instance, in 2017, Thermo Fisher Scientific Inc. launched its new PureLink Fast Low-Endotoxin Plasmid Purification Midi and Maxi Kits, which significantly reduce plasmid purification time to accelerate protein expression.

Transient Protein Expression Market Key Companies to Watch

Agilent Technologies Inc

Company Overview: Agilent is a leader in life sciences, diagnostics and applied chemical markets established on Nov. 18, 1999. The company provides laboratories worldwide with instruments, services, consumables, applications and expertise, enabling customers to gain the insights they seek. With the team of 16,300 employees spread across the world. The majority of research is located in the United States in Santa Clara, California, with additional locations in Europe and Asia.

Product Portfolio: The Company's products include Environmental and Forensics, Food, Pharmaceutical, Diagnostics, Research, Chemical and Energy.

Key Developments: In 2018 Agilent announced to sign a definitive agreement to acquire related businesses with young in Scientific Co. Ltd., a leading distributor of analytical and scientific instruments in South Korea, also is a long-standing distributor of instruments and services for Agilent.

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Target Audience

  • Service Providers/ Buyers
  • Industry Investors/Investment Bankers
  • Education & Research Institutes
  • Research Professionals
  • Emerging Companies
  • Manufacturers

Market Segmentation

Global Transient Protein Expression Market - By Product Type

  • Instruments
    • Automated Transient Protein Expression Systems
    • Manual Transient Protein Expression Systems
  • Reagents
  • Expression Vectors
  • Competent Cells

Global Transient Protein Expression Market – By Application

  • Genomic Research
  • Gene Therapy
  • Bio Production
  • Cancer Research
  • Drug Development

Global Transient Protein Expression Market – By End-user

  • Pharmaceutical and Biotechnology Companies
  • Academic and Research Institutes
  • Clinical Research Organizations

Global Transient Protein Expression Market - By Region

  • North America
  • Europe
  • Asia-Pacific
  • Middle East & Africa
  • South America

Table of Contents

  1. Global Transient Protein Expression Market Methodology and Scope

    1. Research Methodology
    2. Research Objective and Scope of the Report
  2. Global Transient Protein Expression Market – Market Definition and Overview

  3. Global Transient Protein Expression Market – Executive Summary

    1. Market Snippet by Product Type
    2. Market Snippet by Application
    3. Market Snippet by End-user
    4. Market Snippet by Region
  4. Global Transient Protein Expression Market – Market Dynamics

    1. Market Impacting Factors
      1. Driver
        1. Growing adoption of precision medicines
      2. Restraints:
        1.  Lack of requirements of skilled researcher
      3. Opportunity
      4. Impact Analysis
  5. Global Transient Protein Expression Market – Industry Analysis

    1. Porter's Five Forces Analysis
    2. Supply Chain Analysis
    3. PEST Analysis
    4. Pricing Analysis
    5. Regulatory Analysis
    6. Reimbursement Analysis
    7. Unmet Needs
  6. Global Transient Protein Expression Market – COVID-19 Analysis

    1. Analysis of Covid-19 on the Market
      1. Before COVID-19 Market Scenario
      2. Present COVID-19 Market Scenario
      3. After COVID-19 or Future Scenario
    2. Pricing Dynamics Amid Covid-19
    3. Demand-Supply Spectrum
    4. Government Initiatives Related to the Market During Pandemic
    5. Manufacturers Strategic Initiatives
    6. Conclusion 
  7. Global Transient Protein Expression Market – By Product Type

    1. Introduction
      1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type Segment
      2. Market Attractiveness Index, By Product Type Segment
    2.  Instruments*
      1. Introduction
      2. Market Size Analysis, US$ Million, 2018-2028 and Y-o-Y Growth Analysis (%), 2020-2028
      3. Automated Transient Protein Expression Systems
      4. Manual Transient Protein Expression Systems
      5. Reagents
      6. Expression Vectors
      7. Competent Cells
  8. Global Transient Protein Expression Market – By Application

    1. Introduction
      1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
      2. Market Attractiveness Index, By Application
    2. Genomic Research*
      1. Introduction
      2. Market Size Analysis, US$ Million, 2018-2028 and Y-o-Y Growth Analysis (%), 2020-2028
    3. Gene Therapy
    4. Bio Production
    5. Cancer Research
    6. Drug Development
  9. Global Transient Protein Expression Market – By End-user

    1. Introduction
      1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-user
      2. Market Attractiveness Index, By End-user
    2. Pharmaceutical and Biotechnology Companies*
      1. Introduction
      2. Market Size Analysis, US$ Million, 2018-2028 and Y-o-Y Growth Analysis (%), 2020-2028
    3. Academic and Research Institutes
    4. Clinical Research Organizations
  10. Global Transient Protein Expression Market – By Region

    1. Introduction
      1. Market Size Analysis, US$ Million, 2018-2028 and Y-o-Y Growth Analysis (%), 2020-2028, By Region
      2. Market Attractiveness Index, By Region
    2. North America
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-user
      6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. U.S.
        2. Canada
        3. Mexico
    3. Europe
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-user
      6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. Germany
        2. U.K.
        3. France
        4. Italy
        5. Spain
        6. Rest of Europe
    4. South America
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-user
      6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. Brazil
        2. Argentina
        3. Rest of South America
    5. Asia Pacific
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-user
      6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. China
        2. India
        3. Japan
        4. Australia
        5. Rest of Asia Pacific
    6. Middle East and Africa
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-user
  11. Global Transient Protein Expression Market – Competitive Landscape

    1. Key Developments and Strategies
    2. Company Share Analysis
    3. Product Benchmarking
    4. Key Companies to Watch
    5. Company with disruptive technology
    6. Start Up Companies
  12. Global Transient Protein Expression Market- Company Profiles

    1. Agilent Technologies, Inc*
      1. Company Overview
      2. Product Portfolio and Description
      3. Key Highlights
      4. Financial Overview
    2. Promega Corporation
    3. Sino Biological Inc
    4. Genscript Biotech Corporation
    5. Bio-Rad Laboratories Inc
    6. Takara Bio Inc
    7. Thermo Fisher Scientific
    8. Merck KGaA
    9. Qiagen NV
    10. Sigma-Aldrich Corporation
    11. Sino Biopharma(*LIST NOT EXHAUSTIVE)
  13. Global Transient Protein Expression Market – DataM  

    1.       Appendix
    2. About Us and Services
    3. Contact Us

List of Tables & Figures

List of Tables

Table 1 Global Transient Protein Expression Market Value, By Product Type, 2020,2024 & 2028($ Million)

Table 2 Global Transient Protein Expression Market Value, By Application, 2020,2024 & 2028($ Million)

Table 3 Global Transient Protein Expression Market Value, By End-user, 2020,2024 & 2028($ Million)

Table 4 Global Transient Protein Expression Market Value, By Region, 2020,2024 & 2028($ Million)

Table 5 Global Transient Protein Expression Market Value, By Product Type, 2020,2024 & 2028($ Million)

Table 6 Global Transient Protein Expression Market Value, By Product Type, 2018-2028($ Million)

Table 7 Global Transient Protein Expression Market Value, By Application, 2020,2024 & 2028($ Million)

Table 8     Global Transient Protein Expression Market Value, By Application, 2018-2028($ Million)

Table 9 Global Transient Protein Expression Market Value, By End-user, 2020,2024 & 2028($ Million)

Table 10   Global Transient Protein Expression Market Value, By End-user, 2018-2028($ Million)

Table 11    Global Transient Protein Expression Market Value, By Region, 2020,2024 & 2028($ Million)

Table 12   Global Transient Protein Expression Market Value, By Region, 2018-2028($ Million)

Table 13   North America Transient Protein Expression Market Value, By Product Type, 2018-2028($ Million)

Table 14   North America Transient Protein Expression Market Value, By Application, 2018-2028($ Million)

Table 15   North America Transient Protein Expression Market Value, By End-user, 2018-2028($ Million)

Table 16   North America Transient Protein Expression Market Value, By Country, 2018-2028($ Million)

Table 17    South America Transient Protein Expression Market Value, By Product Type, 2018-2028($ Million)

Table 18   South America Transient Protein Expression Market Value, By Application, 2018-2028($ Million)

Table 19   South America Transient Protein Expression Market Value, By End-user, 2018-2028($ Million)

Table 20   South America Transient Protein Expression Market Value, By Country, 2018-2028($ Million)

Table 21   Europe Transient Protein Expression Market Value, By Product Type, 2018-2028($ Million)

Table 22   Europe Transient Protein Expression Market Value, By Application, 2018-2028($ Million)

Table 23   Europe Transient Protein Expression Market Value, By End-user, 2018-2028($ Million)

Table 24   Europe Transient Protein Expression Market Value, By Country, 2018-2028($ Million)

Table 25   Asia-Pacific Transient Protein Expression Market Value, By Product Type, 2018-2028($ Million)

Table 26   Asia-Pacific Transient Protein Expression Market Value, By Application, 2018-2028($ Million)

Table 27   Asia-Pacific Transient Protein Expression Market Value, By End-user, 2018-2028($ Million)

Table 28   Asia-Pacific Transient Protein Expression Market Value, By Country, 2018-2028($ Million)

Table 29   Middle East & Africa Transient Protein Expression Market Value, By Product Type, 2018-2028($ Million)

Table 30   Middle East & Africa Transient Protein Expression Market Value, By Application, 2018-2028($ Million)

Table 31   Middle East & Africa Transient Protein Expression Market Value, By End-user, 2018-2028($ Million)

Table 32   Agilent Technologies, Inc: Overview

Table 33   Agilent Technologies, Inc: Product Portfolio

Table 34   Agilent Technologies, Inc: Key Developments

Table 35   Promega Corporation: Overview

Table 36   Promega Corporation: Product Portfolio

Table 37   Promega Corporation: Key Developments

Table 38   Sino Biological Inc: Overview

Table 39   Sino Biological Inc: Product Portfolio

Table 40   Sino Biological Inc: Key Developments

Table 41   Genscript Biotech Corporation: Overview

Table 42   Genscript Biotech Corporation: Product Portfolio

Table 43   Genscript Biotech Corporation: Key Developments

Table 44   Bio-Rad Laboratories Inc: Overview

Table 45   Bio-Rad Laboratories Inc: Product Portfolio

Table 46   Bio-Rad Laboratories Inc: Key Developments

Table 47   Takara Bio Inc: Overview

Table 48   Takara Bio Inc: Product Portfolio

Table 49   Takara Bio Inc: Key Developments

Table 50   Thermo Fisher Scientific: Overview

Table 51   Thermo Fisher Scientific: Product Portfolio

Table 52   Thermo Fisher Scientific: Key Developments

Table 53   Merck KGaA: Overview

Table 54   Merck KGaA: Product Portfolio

Table 55   Merck KGaA: Key Developments

Table 56   Qiagen NV: Overview

Table 57   Qiagen NV: Product Portfolio

Table 58   Qiagen NV: Key Developments

Table 59   Sigma-Aldrich Corporation: Overview

Table 60   Sigma-Aldrich Corporation: Product Portfolio

Table 61   Sigma-Aldrich Corporation: Key Developments

List of Figures

Figure 1    Global Transient Protein Expression Market Share, By Product Type, 2020 & 2028(%)

Figure 2   Global Transient Protein Expression Market Share, By Application, 2020 & 2028(%)

Figure 3   Global Transient Protein Expression Market Share, By End-user, 2020 & 2028(%)

Figure 4   Global Transient Protein Expression Market Share, By Region, 2020 & 2028(%)

Figure 5   Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 6   Global Transient Protein Expression Market Y-o-Y Growth, By Product Type, 2020 & 2028(%)

Figure 7    Instruments: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 8   Reagents: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 9   Expression Vectors: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 10 Competent Cells: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 11  Global Transient Protein Expression Market Y-o-Y Growth, By Application, 2020 & 2028(%)

Figure 12 Genomic Research: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 13 Gene Therapy: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 14 Bio Production: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 15 Cancer Research: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 16 Drug Development: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 17  Global Transient Protein Expression Market Y-o-Y Growth, By End-user, 2020 & 2028(%)

Figure 18 Pharmaceutical and Biotechnology Companies: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 19 Academic and Research Institutes: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 20 Clinical Research Organizations: Global Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 21 Global Transient Protein Expression Market Y-o-Y Growth, By Region, 2020 & 2028(%)

Figure 22 North America Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 23 North America Transient Protein Expression Market Share, By Product Type, 2020 & 2028(%)

Figure 24 North America Transient Protein Expression Market Share, By Application, 2020 & 2028(%)

Figure 25 North America Transient Protein Expression Market Share, By End-user, 2020 & 2028(%)

Figure 26 North America Transient Protein Expression Market Share, By Country, 2020 & 2028(%)

Figure 27 South America Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 28 South America Transient Protein Expression Market Share, By Product Type, 2020 & 2028(%)

Figure 29 South America Transient Protein Expression Market Share, By Application, 2020 & 2028(%)

Figure 30 South America Transient Protein Expression Market Share, By End-user, 2020 & 2028(%)

Figure 31 South America Transient Protein Expression Market Share, By Country, 2020 & 2028(%)

Figure 32 Europe Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 33 Europe Transient Protein Expression Market Share, By Product Type, 2020 & 2028(%)

Figure 34 Europe Transient Protein Expression Market Share, By Application, 2020 & 2028(%)

Figure 35 Europe Transient Protein Expression Market Share, By End-user, 2020 & 2028(%)

Figure 36 Europe Transient Protein Expression Market Share, By Country, 2020 & 2028(%)

Figure 37 Asia-Pacific Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 38 Asia-Pacific Transient Protein Expression Market Share, By Product Type, 2020 & 2028(%)

Figure 39 Asia-Pacific Transient Protein Expression Market Share, By Application, 2020 & 2028(%)

Figure 40 Asia-Pacific Transient Protein Expression Market Share, By End-user, 2020 & 2028(%)

Figure 41 Asia-Pacific Transient Protein Expression Market Share, By Country, 2020 & 2028(%)

Figure 42 Middle East & Africa Transient Protein Expression Market Value, 2018-2028($ Million)

Figure 43 Middle East & Africa Transient Protein Expression Market Share, By Product Type, 2020 & 2028(%)

Figure 44 Middle East & Africa Transient Protein Expression Market Share, By Application, 2020 & 2028(%)

Figure 45 Middle East & Africa Transient Protein Expression Market Share, By End-user, 2020 & 2028(%)

Figure 46 Agilent Technologies, Inc: Financials

Figure 47 Promega Corporation: Financials

Figure 48 Sino Biological Inc: Financials

Figure 49 Genscript Biotech Corporation: Financials

Figure 50 Bio-Rad Laboratories Inc: Financials

Figure 51 Takara Bio Inc: Financials

Figure 52 Thermo Fisher Scientific: Financials

Figure 53 Merck KGaA: Financials

Figure 54 Qiagen NV: Financials

Figure 55 Sigma-Aldrich Corporation: Financials

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