Transcatheter Aortic Valve Replacement (TAVR) Market - Size, Share and Forecast (2019-2026)

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In April 2019, the FDA approved Boston Scientific's LOTUS Edge Aortic Valve System in patients at high risk for surgical valve replacement via open heart surgery.

Transcatheter Aortic Valve Replacement (TAVR) Market Overview

Transcatheter aortic valve replacement (TAVR) is a minimally invasive surgical procedure for heart disease in which the valve is used to replace the old or damaged heart valve. This procedure helps to reduce severe degenerative aortic stenosis and upsurges the survival rate of patients.

The global transcatheter aortic valve replacement (TAVR) market size was worth $ XX billion in 2018 and is forecasted to reach $ XX billion by 2026, at a CAGR of XX% during the forecast period (2019-2026).

Transcatheter Aortic Valve Replacement (TAVR) Market Dynamics

The global transcatheter aortic valve replacement (TAVR) market is driven by several growth factors such as rising prevalence of cardiovascular disorders such as heart failure (HF), coronary artery diseases (CAD), and hypertension. Cardiovascular diseases (CVDs) cause improper functioning of aortic valves, hence fuelling the demand for efficient valve replacement procedure. According to the National Health and Nutrition Examination Survey (NHANES) data (2016), an estimated 6.2 million American adults ≥20 years of age (2.2%) had heart failure between 2013 and 2016 compared with an estimated 5.7 million between 2009 and 2012. More than 5.7 million Americans suffer from heart failure, and there are approximately 915,000 new patients diagnosed with the disease annually. According to the World Health Organization (WHO), the number of people suffering cardiovascular disorders will surge to 22.2 million by 2030 globally.

In addition, rising implementation of minimally intrusive processes over traditional surgical open-heart procedures, increasing studies on transcatheter aortic valve replacement (TAVR) for low risk of infection, minimal blood loss is further boosting the market growth. Transcatheter aortic valve replacement (TAVR) has been studied as an alternative to surgical aortic valve replacement in high and intermediate-risk surgical patients for more than five years. In May 2019, a new clinical trial, one of two studies on the topic presented at the American Association for Thoracic Surgery's 99th Annual Meeting, found the procedure to be equivalent or potentially preferable to surgical aortic valve replacement (SAVR) for low risk patients.

Increasing advancement in technology, new product launch, rising funding for research & development activities, increasing collaboration and mergers by major players are also some of the factors boosting the growth of the TAVR market globally. For instance, in March 2017, Boston Scientific Corporation acquired Symetis SA for US$ 435 million to sell the ACURATE TA™ and ACURATE neo™/TF™ valve  systems in Europe and in other geographies outside of the United States for the treatment of patients suffering from symptomatic aortic valve stenosis globally.

In August 2017, Edwards Lifesciences Corporation focused on R&D to launch Edwards Sapien 3 Ultra System and Centera which include Axela sheath technology and on-balloon delivery design that make the procedure faster and reduce the possibility of any error.

Transcatheter Aortic Valve Replacement (TAVR) Market Segment Analysis

By type, the global transcatheter valve replacement (TAVR) market is segmented into transaortic implantation, transfemoral (TF) implantation, and transapical (TA) implantation. Among these, transfemoral (TF) implantation accounted for the largest market share in 2018 and estimated to grow at a significant growth rate during the forecast period. Transfemoral implantation is a standardized and a consistent procedure in which an artificial valve is inserted through the femoral blood vessel with the minimally invasive procedure and negligible anesthesia. The transfemoral implantation procedure is the most common catheter-based approach and is performed in more than 80% of the transcatheter valve replacement (TAVR) cases, globally.

In addition, due to advanced technological systems and various platforms by key players, the segment is growing further during the forecast period. For instance, in September 2018, Israel cardiovascular device developer Cardiovalve launched both the Ahead US and Ahead EU multicenter studies of its Cardiovalve transfemoral mitral valve replacement system. In September 2017, Integrum launched the OPRA Implant System Platform G for transfemoral patients. The new platform is CE labeled and approved by the FDA improves the mechanical performance of the system, simplifies the surgical procedure and enhances osseointegration. In September 2014, Symetis SA, a European developer of transcatheter aortic valve implantation (TAVI) systems, launched ACURATE neo™, its 15F compatible transfemoral TAVI system.

Transcatheter Aortic Valve Replacement (TAVR) Market Geographical Analysis

North America is dominating the transcatheter aortic valve replacement (TAVR) market in 2018 and estimated to hold largest market size over the forecast period (2019-2026), owing to rising prevalence of cardiovascular disease (CVD). It is one of the major cause of death, accounted for 840,678 deaths in the US in 2016, approx. 1 of every 3 deaths. Between 2013 and 2016, 121.5 million American adults had some form of cardiovascular disease. As per the American Heart Association, 2019, 116.4 million or 46% of the US adults are estimated to have hypertension. In 2016, Coronary Heart Disease was the leading cause (43.2%) of deaths attributable to cardiovascular disease in the US, followed by stroke (16.9%), High Blood Pressure (9.8%), Heart Failure (9.3%), diseases of the arteries (3.0%), and other cardiovascular diseases (17.7%).

In addition, rising adoption of technologically advanced products, increasing mergers & acquisitions among major players, and favorable reimbursement policies are some of the factors leading to the growth of the TAVR market in this region. For instance, government organizations in the United States such as Centers for Medicare & Medicaid Services (CMS) help patients to opt for transcatheter aortic valve replacement procedure. According to the Journal of the American College of Cardiology, in the United States, 25 000 transcatheter valve implantation (TAVI) procedures were performed in 2015, and this figure is estimated to reach 100 000 procedures by 2020.

Europe transcatheter aortic valve replacement (TAVR) market is growing at the highest growth rate during the forecast period (2019-2026) due to the rising cases of severe aortic stenosis along with growing elderly population, and high adoption rate of advanced transcatheter aortic valves. In Germany, all transcatheter valve implantation (TAVI) and surgical aortic valve replacement (SAVR) procedures are registered within an obligatory quality assurance program led by the independent Institute for Applied Quality Improvement and Research in Health Care (AQUA). According to the AQUA reports, the annual number of SAVR procedures decreased from 11,205 in 2008 (mean age, 69.8 years) to 9,953 in 2014 (mean age, 68.5 years). On the other hand, the number of transcatheter valve implantation (TAVI) procedures has increased 20-fold, from 637 in 2008 (mean age, 81.6 years) to 13,264 in 2014 (mean age, 80.9 years) and has exceeded the annual numbers of isolated SAVR since 2013.

In Europe, countries such as France, Germany, and Italy are leading markets for TAVR with rising aortic valve procedure, and technological advancement in the devices. For instance, in 2015, according to the National Center for Biotechnology Information (NCBI), around 31,000 aortic valve procedures were performed in Germany, owing to advancements in aortic valve replacement procedure, making it the most preferred destination for valve replacement implantation. In August 2016, Medtronic reveived CE mark approval for the self-expanding, recapturable and repositionable CoreValve Evolut R System to treat aortic stenosis patients who are at intermediate risk for open-heart surgery. The Evolut R System is the first transcatheter aortic valve replacement (TAVR or TAVI) device to obtain this expanded indication in Europe.

Transcatheter Aortic Valve Replacement (TAVR) Market Competitive Landscape

The Transcatheter Aortic Valve Replacement (TAVR) market is dominated by few major players including Medtronic plc, Boston Scientific Corporation, St. Jude Medical, Inc., Edwards Lifesciences Corporation, HLT, Inc., JenaValve Technology, Inc., Direct Flow medical, Inc., Meril Life Sciences Pvt. Ltd., Transcatheter Technologies GmbH, SYMETIS SA, among others. The key players are also adopting various growth strategies such as mergers & acquisitions, partnerships, and collaborations which are contributing to the growth of the Transcatheter Aortic Valve Replacement (TAVR) market globally. The players are also focusing on product approvals and developing innovative products to strengthen their product portfolio that intensifies the market competition.

In June 2019, Meril Life Sciences became the first Indian company to market and distribute its indigenously designed and patented TAVR technology, MyvalTM -THV system, to the European Union and other countries. The product has received the coveted CE approval in April 2019.

In April 2019, the FDA approved Boston Scientific's LOTUS Edge Aortic Valve System in patients at high risk for surgical valve replacement via open heart surgery.

In August 2017, Edwards Lifesciences Corporation focused on R&D to launch Edwards Sapien 3 Ultra System and Centera. These include Axela sheath technology and on-balloon delivery design that make the procedure faster and reduce the possibility of any error. This would enable the company to be more competitive with other players such as Medtronic, Boston Scientific Corporation, and Abbott.

In July 2017, Medtronic plc launched CoreValve Evolut PRO valve system in Europe for the treatment of aortic stenosis. The system will offer innovative medical technology for surgical treatment of cardiovascular disease, which estimated to bolster company’s growth in the field of cardiac surgeries.

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Transcatheter Aortic Valve Replacement (TAVR) Market

  1. Global Transcatheter Aortic Valve Replacement (TAVR) Market Methodology and Scope

    1. Research Methodology
    2. Research Objective and Scope of the Report
  2. Global Transcatheter Aortic Valve Replacement (TAVR) Market – Market Definition and Overview

  3. Global Transcatheter Aortic Valve Replacement (TAVR) Market – Executive Summary

    1. Market Snippet by Type
    2. Market Snippet by End-User
  4. Global Transcatheter Aortic Valve Replacement (TAVR) Market Dynamics

    1. Market Impacting Factors
      1. Drivers
        1. Rising Prevalence of Cardiovascular Diseases
        2. Increasing Technological Advancement in Devices
      2. Restraints
        1. High Cost of the devices
      3. Opportunity
      4. Impact Analysis
  5. Global Transcatheter Aortic Valve Replacement (TAVR) Market – Industry Analysis

    1. Porter's Five Forces Analysis
    2. Regulatory Analysis
    3. Supply Chain Analysis
    4. Pricing Analysis
  6. Global Transcatheter Aortic Valve Replacement (TAVR) Market – By Type

    1. Introduction
    2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type Segment
    3. Market Attractiveness Index, By Type Segment
      1. Transfemoral (TF) Implantation*
        1. Introduction
        2. Market Size Analysis, US$ Mn, 2016-2025 and Y-o-Y Growth Analysis (%), 2018-2026
      2. Transaortic Implantation
      3. Transapical (TA) Implantation
  7. Global Transcatheter Aortic Valve Replacement (TAVR) Market – By End-User

    1. Introduction
    2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User Segment
    3. Market Attractiveness Index, By End-User Segment
      1. Hospitals*
        1. Introduction
        2. Market Size Analysis, US$ Mn, 2016-2025 and Y-o-Y Growth Analysis (%), 2018-2026
      2. Cardiac catheterization laboratory
      3. Ambulatory surgical centers 
      4. Others
  8. Global Transcatheter Aortic Valve Replacement (TAVR) Market – By Region

    1. Introduction
      1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Region
      2. Market Attractiveness Index, By Region
    2. North America
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. U.S.
        2. Canada
        3. Mexico
    3. Europe
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. Germany
        2. U.K.
        3. France
        4. Italy
        5. Spain
        6. Rest of Europe
    4. South America
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. Brazil
        2. Argentina
        3. Rest of South America
    5. Asia Pacific
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. China
        2. India
        3. Japan
        4. Australia
        5. Rest of Asia Pacific
    6. Middle East and Africa
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
  9. Global Transcatheter Aortic Valve Replacement (TAVR) Market – Competitive Landscape

    1. Competitive Scenario
    2. Market Positioning/Share Analysis
    3. Mergers and Acquisitions Analysis
  10. Company Profiles

    1. St. Jude Medical, Inc.*
      1. Company Overview
      2. Product Portfolio and Description
      3. Key Highlights
      4. Financial Overview
    2. Medtronic plc
    3. Boston Scientific Corporation
    4. Edwards Lifesciences Corporation
    5. HLT, Inc.
    6. JenaValve Technology, Inc.
    7. Direct Flow medical, Inc.
    8. Meril Life Sciences Pvt. Ltd.
    9. Transcatheter Technologies GmbH
    10. SYMETIS SA
  11. Global Transcatheter Aortic Valve Replacement (TAVR) Market – Premium Insights

  12. Global Transcatheter Aortic Valve Replacement (TAVR) Market – DataM

    1. Appendix
    2. About Us and Services
    3. Contact Us

List of Tables

Table 1 Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Type, 2018,2022 & 2026 ($ Million)

Table 2 Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, By End-User, 2018,2022 & 2026 ($ Million)

Table 3 Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Region, 2018,2022 & 2026 ($ Million)

Table 4 Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Type, 2018,2022 & 2026 ($ Million)

Table 5 Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Type, 2017-2026 ($ Million)

Table 6 Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, By End-User, 2018,2022 & 2026 ($ Million)

Table 7 Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, By End-User, 2017-2026 ($ Million)

Table 8 Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Region, 2018,2022 & 2026 ($ Million)

Table 9 Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Region, 2017-2026 ($ Million)

Table 10 North America Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Type, 2017-2026 ($ Million)

Table 11 North America Transcatheter Aortic Valve Replacement (TAVR) Market Value, By End-User, 2017-2026 ($ Million)

Table 12 North America Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Country, 2017-2026 ($ Million)

Table 13 South America Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Type, 2017-2026 ($ Million)

Table 14 South America Transcatheter Aortic Valve Replacement (TAVR) Market Value, By End-User, 2017-2026 ($ Million)

Table 15 South America Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Country, 2017-2026 ($ Million)

Table 16 Europe Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Type, 2017-2026 ($ Million)

Table 17 Europe Transcatheter Aortic Valve Replacement (TAVR) Market Value, By End-User, 2017-2026 ($ Million)

Table 18 Europe Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Country, 2017-2026 ($ Million)

Table 19 Asia-Pacific Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Type, 2017-2026 ($ Million)

Table 20 Asia-Pacific Transcatheter Aortic Valve Replacement (TAVR) Market Value, By End-User, 2017-2026 ($ Million)

Table 21 Asia-Pacific Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Country, 2017-2026 ($ Million)

Table 22 Middle East & Africa Transcatheter Aortic Valve Replacement (TAVR) Market Value, By Type, 2017-2026 ($ Million)

Table 23 Middle East & Africa Transcatheter Aortic Valve Replacement (TAVR) Market Value, By End-User, 2017-2026 ($ Million)

Table 24 Medtronic plc: Overview

Table 25 Medtronic plc: Product Portfolio

Table 26 Medtronic plc: Key Developments

Table 27 Boston Scientific Corporation: Overview

Table 28 Boston Scientific Corporation: Product Portfolio

Table 29 Boston Scientific Corporation: Key Developments

Table 30 St. Jude Medical, Inc.: Overview

Table 31 St. Jude Medical, Inc.: Product Portfolio

Table 32 St. Jude Medical, Inc.: Key Developments

Table 33 Edwards Lifesciences Corporation: Overview

Table 34 Edwards Lifesciences Corporation: Product Portfolio

Table 35 Edwards Lifesciences Corporation: Key Developments

Table 36 HLT, Inc.: Overview

Table 37 HLT, Inc.: Product Portfolio

Table 38 HLT, Inc.: Key Developments

Table 39 JenaValve Technology, Inc.: Overview

Table 40 JenaValve Technology, Inc.: Product Portfolio

Table 41 JenaValve Technology, Inc.: Key Developments

Table 42 Direct Flow medical, Inc.: Overview

Table 43 Direct Flow medical, Inc.: Product Portfolio

Table 44 Direct Flow medical, Inc.: Key Developments

Table 45 Meril Life Sciences Pvt. Ltd.: Overview

Table 46 Meril Life Sciences Pvt. Ltd.: Product Portfolio

Table 47 Meril Life Sciences Pvt. Ltd.: Key Developments

Table 48 Transcatheter Technologies GmbH: Overview

Table 49 Transcatheter Technologies GmbH: Product Portfolio

Table 50 Transcatheter Technologies GmbH: Key Developments

Table 51 SYMETIS SA: Overview

Table 52 SYMETIS SA: Product Portfolio

Table 53 SYMETIS SA: Key Developments

 List of Figures

Figure 1 Global Transcatheter Aortic Valve Replacement (TAVR) Market Share, By Type, 2018 & 2026 (%)

Figure 2 Global Transcatheter Aortic Valve Replacement (TAVR) Market Share, By End-User, 2018 & 2026 (%)

Figure 3 Global Transcatheter Aortic Valve Replacement (TAVR) Market Share, By Region, 2018 & 2026 (%)

Figure 4 Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 5 Global Transcatheter Aortic Valve Replacement (TAVR) Market Y-o-Y Growth, By Type, 2018-2026 (%)

Figure 6 Transfemoral (TF) Implantation: Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 7 Transaortic Implantation: Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 8 Transapical (TA) Implantation: Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 9 Global Transcatheter Aortic Valve Replacement (TAVR) Market Y-o-Y Growth, By End-User, 2018-2026 (%)

Figure 10 Hospitals: Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 11 Cardiac catheterization laboratory: Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 12 Ambulatory surgical centers : Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 13 Others: Global Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 14 Global Transcatheter Aortic Valve Replacement (TAVR) Market Y-o-Y Growth, By Region, 2018-2026 (%)

Figure 15 North America Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 16 North America Transcatheter Aortic Valve Replacement (TAVR) Market Share, By Type, 2018 & 2026 (%)

Figure 17 North America Transcatheter Aortic Valve Replacement (TAVR) Market Share, By End-User, 2018 & 2026 (%)

Figure 18 North America Transcatheter Aortic Valve Replacement (TAVR) Market Share, By Country, 2018 & 2026 (%)

Figure 19 South America Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 20 South America Transcatheter Aortic Valve Replacement (TAVR) Market Share, By Type, 2018 & 2026 (%)

Figure 21 South America Transcatheter Aortic Valve Replacement (TAVR) Market Share, By End-User, 2018 & 2026 (%)

Figure 22 South America Transcatheter Aortic Valve Replacement (TAVR) Market Share, By Country, 2018 & 2026 (%)

Figure 23 Europe Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 24 Europe Transcatheter Aortic Valve Replacement (TAVR) Market Share, By Type, 2018 & 2026 (%)

Figure 25 Europe Transcatheter Aortic Valve Replacement (TAVR) Market Share, By End-User, 2018 & 2026 (%)

Figure 26 Europe Transcatheter Aortic Valve Replacement (TAVR) Market Share, By Country, 2018 & 2026 (%)

Figure 27 Asia-Pacific Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 28 Asia-Pacific Transcatheter Aortic Valve Replacement (TAVR) Market Share, By Type, 2018 & 2026 (%)

Figure 29 Asia-Pacific Transcatheter Aortic Valve Replacement (TAVR) Market Share, By End-User, 2018 & 2026 (%)

Figure 30 Asia-Pacific Transcatheter Aortic Valve Replacement (TAVR) Market Share, By Country, 2018 & 2026 (%)

Figure 31 Middle East & Africa Transcatheter Aortic Valve Replacement (TAVR) Market Value, 2017-2026 ($ Million)

Figure 32 Middle East & Africa Transcatheter Aortic Valve Replacement (TAVR) Market Share, By Type, 2018 & 2026 (%)

Figure 33 Middle East & Africa Transcatheter Aortic Valve Replacement (TAVR) Market Share, By End-User, 2018 & 2026 (%)

Figure 34 Medtronic plc: Financials

Figure 35 Boston Scientific Corporation: Financials

Figure 36 St. Jude Medical, Inc.: Financials

Figure 37 Edwards Lifesciences Corporation: Financials

Figure 38 HLT, Inc.: Financials

Figure 39 JenaValve Technology, Inc.: Financials

Figure 40 Direct Flow medical, Inc.: Financials

Figure 41 Meril Life Sciences Pvt. Ltd.: Financials

Figure 42 Transcatheter Technologies GmbH: Financials

Figure 43 SYMETIS SA: Financials

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