Protein Labeling Market Size, Share, Industry, Forecast and outlook (2024-2031)

Protein Labeling Market is segmented By Product Type (Kits, Reagents, Services), By Labeling Type (Vitro labeling, Vivo labeling, Biorthogonal Labeling), By Application (Cell-Based Assay, Immunological Techniques, Protein Microarrays, Mass Spectroscopy, Fluorescence Microscopy), By End-User (Hospitals, Research laboratories, Diagnostic Centers, Others), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2024-2031

Protein Labeling Market Report Overview

The Global Protein Labeling Market is estimated to grow at a CAGR of 6.4% during the forecast period (2024-2031)

Biological research requires the use of molecular labels that are covalently attached to a protein of interest to facilitate the purification or detection of the labeled protein and its binding partners. The primary purpose of protein labeling is monitoring the biological process, reliable quantification of compounds, specific detection of protein modifications and isoforms in multiplexed samples, enhancement of detection sensitivity, and simplification of detection workflows.

Protein Labeling Market Summary

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Protein Labeling Market Dynamics and Trends

The major factors driving the global protein labeling market are an increase in the number of chronic diseases globally, rising research and development expenditure, and the adoption of bioengineering techniques. An increase in novel product launches contributes to the growth of the protein labeling market.

The rising genome sequencing and proteomics research and the adoption of sophisticated bioengineering techniques are expected to drive the market’s growth.

The rising adoption of these protein labeling products for post-translational modification studies in the investigation of biological functions as well as normal cell functioning, the rising adoption of sophisticated bioengineering techniques in various technologies, and the growth in the prevalence of chronic diseases such as cancer and the need for diagnosis drive the protein labeling market. An increase in chronic diseases globally is also aiding the market growth. There has been an increase in R&D activities by many healthcare companies to develop novel products.

Test that includes western blotting, ELISA, immunohistochemistry, immunocytochemistry, and flow cytometry requires protein labeling methods for various medical and clinical studies. There is an availability of multiple labels in the market for multiple applications, and the type of name and labeling strategy used must be carefully selected for each application. The surge in demand for genome sequencing and proteomics research is fueling the market’s growth. Moreover, the increase in research and development of novel vaccines and the availability of technologically advanced products by key players are also expected to play a vital role in the market’s growth. 

Various novel product launches, regulatory approvals, and research studies contribute to the market’s growth. For instance, on September 17, 2021, PerkinElmer, Inc. announced its completion of the acquisition of BioLegend, a life science reagents and antibodies provider, for approximately $5.25 billion in total consideration. This acquisition expands the life science franchise of PerkinElmer into high-growth areas like proteogenomics, cytometry, multiplex assays, magnetic cell separation, recombinant proteins, and bioprocessing.

The skillful professional’s limited availability is expected to hamper the market’s growth.

However, the limited availability of skillful professionals in the current scenario, increased competition among key players for launching advanced products, and limited product applications may hinder the growth of the market.

The high cost of protein labeling is also a leading factor for restrained growth, as chemical labeling has a drawback that the protein that has been modified can lose one or more activities. So, the labeled protein’s activity should be tested relative to unlabeled protein. Metabolic labeling also needs purification of the radioactive protein, and over the extended use of cold room equipment and centrifuges, it is difficult to consist the radioactivity.

COVID-19 Impact on Protein Labeling Market Growth

The pandemic has negatively impacted global financial expectations, operations, and crisis response strategy. The COVID-19 outbreak has severely impacted the healthcare industry. The protein labeling market has experienced huge losses due to COVID, as various research and clinical trials got postponed due to the increasing number of COVID cases. Various initiatives, product launches, innovations, collaborations, and mergers are happening worldwide, boosting the market’s growth. For instance, on July 28, 2021, Promega Corporation announced that U.S. FDA had cleared its Promega OncoMate MSI Dx Analysis System. Pathologists and oncologists in the US can utilize microsatellite instability (MSI) diagnostic for screening Lynch syndrome in colorectal cancer patients.

Protein Labeling Market Segments

The reagent segment is expected to grow at the fastest CAGR during the forecast period (2024-2031)

The reagent segment is the highest market holder in the global protein labeling market. The global protein labeling market is segmented based on product type as kits, reagents, and services. The reagents segment is the largest market shareholder due to its high demand and usage, increasing prevalence of cancer, and rising adoption of these for protein labeling products. Reagents are further sub-segmented into probes, biotin, proteins, enzymes, and others. These reagents hold the largest market share due to increased demand for peptide-binding agents and increased research and development activities, which are expected to remain high during the forecast period.

The protein labeling reagents are developed to label target proteins selectively. These products are classic dyes, biotinylation reagents, radioisotope labels, fluorescent labels, assays, molecular probes, and labeling kits. Fluorophores, stable isotopes, and mass tags are three important tags implemented during protein labeling. Western blotting, immunohistochemistry, ELISA, immunocytochemistry, and flow cytometry require protein labeling methods for various medical and clinical studies. There is an availability of multiple labels in the market for multiple applications, and the type of name and labeling strategy used must be carefully selected for each application. 

The growing number of regulatory approvals, technological advancements, product launches, and research/clinical trial studies drive the market’s growth. For instance, on July 28, 2021, PerkinElmer, Inc announced the launch of its four-novel ready-to-use AlphaLISA KRAS kits, developed to provide scientists with a better understanding of complex KRAS protein structures as well as mutations so that potential new therapeutic candidates identification gets more easy, precise and quick for a broad range of prevalent cancers.

Protein Labeling Market Geographical Share

North America holds the largest market share in the global protein labeling market.

North America dominates the global protein labeling market, primarily due to its large population, excellent medical infrastructure, and rising number of chronic diseases like cancer. The market is expected to grow at a relatively high pace during the forecast period due to healthcare expenditure in the US. The market’s significant size is attributed to the high medical expenditure. 

Increasing expenditure on healthcare and raising awareness among people are also contributing to the market’s growth in this region. Advancement of products for various applications, including cell-based assay, immunological techniques, mass spectroscopy, protein microarrays, fluorescence microscopy, increase in pharmaceutical establishment across the region, government approvals, and key players in the region are contributing to the growth of the protein labeling market. 

Moreover, the growing number of product launches is responsible for the market’s growth. Many key developments, regulatory approvals, technological advancements, collaborations, and agreements are taking place in this region. For instance, on January 11, 2022, Merck, a science and technology company, announced its Stable Isotope Center of Excellence expansion in Miamisburg, Ohio. The expansion strengthens the continued commitment of the company to this product category, which shows growing utility in industrial, diagnostic, and research applications. 

Protein Labeling Companies & Competitive Landscape

The protein labeling market is moderately competitive with local and global companies’ presence. Thermo Fisher Scientific, Merck KGaA, PerkinElmer Inc., GE Healthcare, Qiagen N.V., New England Biolabs, SeraCare Life Sciences Inc., Promega Corporation, Bio-Rad Laboratories, Inc., Agilent Technologies, and more. The key players are adopting various growth strategies such as product launches, mergers & acquisitions, partnerships, and collaborations, contributing to the market’s growth. For instance, on June 7, 2021, Thermo Fisher Scientific announced its agreement with Advanced Electrophoresis Solutions Ltd (AES), protein imaging technologies specialists, to combine mass spectrometry (MS) with essential protein separation techniques for the advancement of therapeutic protein development via streamlined characterization. 

Thermo Fisher Scientific.

Overview: This is a company that supplies a variety of scientific or analytical instruments, lab reagents & consumables, and some scientific software services. It was founded in 1956 and headquartered in Waltham, Massachusetts, U.S.  

Product Portfolio: 

Fluorescent Protein Labeling Kits: The fluorescent dye attachment to proteins or other biomolecules is a general strategy used to better understand protein function and structure. These fluorescent proteins can be utilized in various applications, like immunochemistry, receptor labeling, cell tracing, and fluorescence spectroscopy.

Key Developments: On October 31, 2022, Thermo Fisher Scientific Inc. announced entering into a definitive acquisition agreement with The Binding Site Group, a specialty diagnostics company that provides specialized diagnostic instruments and assays, from a group of shareholders led by Nordic Capital, a European private equity firm. 

The global protein labeling market report would provide access to approx.: 45+ market data tables, 40+ figures, and 200 (approximate) pages.