Premenstrual Syndrome Treatment Market

SKU: DMPH2390 | Last Updated On: Oct 28 2022 | Available Formats

> Premenstrual Syndrome Treatment Market Expected to reach at a high CAGR of 4% by 2029:

Premenstrual Syndrome Treatment Market is segmented By Drug Class (Analgesics, Antidepressants, Oral Contraceptives, Ovarian Suppression Agents, Gonadotropin-releasing hormone (GnRH) Analogues, Estrogen-only patches & implants, Selective serotonin reuptake inhibitors (SSRIs), Others), By Distribution Channel (Hospital Pharmacies, Drug Stores & Retail Pharmacies, Online Providers, Others), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2022-2029

Premenstrual Syndrome Treatment Market Size Share Growth Demand Outlook

Premenstrual Syndrome Treatment Market size was valued USD 1,367 million in 2021 and is estimated to reach USD 1,829 million by 2029, growing at a CAGR of 4.1% during the forecast period (2022-2029). Premenstrual Syndrome is a combination of physical and emotional symptoms, including mood swings, body pain, fatigue, tender breasts, food cravings, fatigue, irritability, and depression. It arises around the end of the luteal phase and dissipates with menstruation or briefly thereafter. It is most commonly observed among women with a high level of stress, depression, cyclic changes in the menstruation cycle, and chemical changes in the brain.

As per DataM Intelligence, Premenstrual Syndrome Treatment Market study analysis offers an in-depth outlook on the market containing quantitative and qualitative data. It gives an outlook and forecast of the global market based on market segmentation. It also provides global Premenstrual Syndrome Treatment Market size, and growth, along with the latest trends, opportunities, and forecast till 2029 for the global market with esteem to major countries such as the United States, Canada, Brazil, Germany, Italy, Spain, United Kingdom, Russia, European countries, United Arab Emirates, Saudi Arabia, South Africa, Japan, China, India, South Korea, Australia, and rest of the countries over the globe.

Among all regions, the North American region is expected to hold the largest share of the global market over the forecast period. Premenstrual Syndrome Treatment Market in the United States and Canada produces the utmost share. Whereas the European Premenstrual Syndrome Treatment Market is projected to continue its presence globally during the period of 2022- 2029.

Premenstrual Syndrome Treatment Market Scope



Market CAGR


Segments Covered

By Drug Class, By Distribution Channel, and By Region

Report Insights Covered

Competitive Landscape Analysis, Company Profile Analysis, Market Size, Share, Growth, Demand, Recent Developments, Mergers and acquisitions, New Product Launches, Growth Strategies, Revenue Analysis, and Other key insights.

Fastest Growing Region

Asia Pacific

Largest Market Share 

North America

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Market Dynamics

The global premenstrual syndrome treatment market is growing due to several factors such as growing awareness towards the significance of premenstrual syndrome treatment globally and rising government and non-government organizations initiatives doe women healthcare and various developments of new therapies.

Larger targeted population and new developments in therapies are expected to drive market growth.

The larger targeted population drives the market as it is the most common health problem in women of reproductive age. According to Petranka Chumpalova et al. 2020, in a study published in the Annals of General Psychiatry journal, 90% of women of reproductive age experience several premenstrual symptoms varying from mild to severe.  Approximately 20-40% of those women suffer from Premenstrual Syndrome, and around 2–8% of those women suffer from the premenstrual dysphoric disorder (PMDD) worldwide.

The undergoing research and development activities to develop therapies for Premenstrual Syndrome shall positively impact the market. For instance, the clinical studies demonstrated that the administration of the PH80-PMD (Pherin Pharmaceuticals) administered intranasally PRN decreased moderate and severe premenstrual symptoms significantly better compared to the placebo during the critical premenstrual days of the cycle without the need for chronic administration.

Asarina Pharma is developing a potential therapy for the treatment of Premenstrual Dysphoric Disorder (PMDD), a severe and disabling form of premenstrual syndrome. Its lead product, i.e., Sepranolone, had met its primary safety and efficacy endpoints in a new Phase II study involving 120 women with Premenstrual Dysphoric Disorder. Sepranolone is a proprietary, first-in-class, endogenous, small molecule that acts as a GABA-A modulating steroid antagonist (GAMSA).

There is an increase in awareness regarding the diagnosis, treatment, and reimbursement of premenstrual syndrome worldwide. For instance, in June 2019, Premenstrual dysphoric disorder (PMDD) has been given its own classification code and, for the first time, classified clearly as a gynecological, not mental, disease in the WHO’s new International Classification of Diseases, ICD-11. The inclusion of PMDD in ICD-11 is an important indicator of the growing medical awareness of PMDD worldwide and a growing scientific consensus that PMDD is a hormonal, not psychiatric condition. PMDD is mentioned in the WHO’s present ICD-10, but indirectly as a sub-classification under ‘Premenstrual tension syndrome.

Side-effects associated with use of therapies are expected to hamper the market growth.

However, the side-effects associated with the use of therapies for premenstrual syndrome shall hider market growth. For instance, the use of selective serotonin reuptake inhibitors (SSRIs) results in adverse events such as nausea, asthenia, fatigue, sexual dysfunction, and decreased energy. Gonadotropin-releasing hormones (GnRH) analogs are not recommended for the long term as these analogs lead to adverse effects on bone density and increase the risk of developing bone thinning.

Industry Analysis

The global premenstrual syndrome treatment market provides in-depth analysis of the market based on various industry factors such as Porter’s Five Forces, Regulatory Analysis, Supply Chain Analysis, Pricing Analysis.

Segment Analysis

Product type segment is expected to hold the largest market share in global premenstrual syndrome treatment market

The premenstrual syndrome treatment market is segmented based on product type as analgesics, antidepressants, oral contraceptives agents, ovarian suppression agents, gonadotropin-releasing hormone (GnRH) analogs, estrogen-only patches & implants, selective serotonin reuptake inhibitors (SSRIs), and others. The analgesics segment accounts for the highest market share owing to the higher uptake of analgesics as it is the mainstay treatment for premenstrual syndrome. Various analgesics such as ibuprofen, acetaminophen, diclofenac, naproxen is used for the management of premenstrual syndrome. These analgesics are effective in reducing stomach cramps, headache, muscle pain, joint pain and others.

The oral contraceptive agent segment is expected to have positive market growth due to the rising usage of oral contraceptive agents to manage the physical and psychiatric symptoms of premenstrual syndrome. The oral contraceptive agents, including the levonorgestrel/ Ethinyl estradiol, drospirenone and others, are used to even out the ovarian hormone fluctuations. Clinical studies have demonstrated that the administration of 90 mcg levonorgestrel/20 mcg Ethinyl estradiol resulted in improvement in depressive and physical symptoms. 

The antidepressant segments account for the significant market share over the forecasted period. The antidepressants act by increasing the brain chemicals, including opioids, serotonin, and others hampered due to the ovarian hormones. Serotonin reuptake inhibitors (SSRIs) are recommended for treating the mood changes associated with Premenstrual Syndrome. The market is dominated by the availability of several serotonin reuptake inhibitors, including Fluoxetine (Prozac), paroxetine (Paxil), Sertraline (Zoloft), citalopram (Celexa) and escitalopram (Lexapro) for the treatment of psychiatric symptoms associated with Premenstrual Syndrome. The clinical studies demonstrated that these five serotonin reuptake inhibitors (SSRIs) have statistically significant benefits on patient-reported symptoms when taken continuously or only during the luteal phase.

Further, the market is also classified based on distribution channel as hospital pharmacies, drug stores & retail pharmacies, online providers, and others. The drug stores & retail pharmacies segment are expected to have the highest market share due to many drug stores & retail pharmacies worldwide. The majority of the drugs being used for the premenstrual syndrome are the counter drugs, which are easily available over the counter without a prescription.  It is further expected that the drug stores & retail pharmacies segment shall lose its market share with the rising growth of online providers worldwide over the forecasted period.

The online provider's segment is expected to have significant market growth due to the growing preference for online purchasing of drugs compared to the traditional methods, including the drug stores & retail pharmacies and hospital pharmacies. The rising awareness regarding online providers, growing internet users, and digital transformation shall stimulate market growth. Hence, it is expected that online providers shall account for the highest market share over the forecasted period.

Geographical Analysis

North America region holds the largest market share in the global premenstrual syndrome treatment market

By region, the premenstrual syndrome treatment market is segmented into North America, South America, Europe, Asia-Pacific, Middle-East, and Africa. Among all of the regions, North America dominated the premenstrual syndrome treatment market due to the rising prevalence of premenstrual syndrome. According to the American Academy of Family Physicians, in 2020 approximately 90% of childbearing age women experience premenstrual symptoms, and less than 10% are diagnosed with the premenstrual dysphoric disorder (PMDD). The growing awareness regarding women's health shall stimulate market growth. For instance, The Office on Women's Health (OWH) within the U.S. Department of Health and Human Services (HHS) is involved in creating awareness by addressing the critical women's health issues. It helps inform and advance policies, educate professionals and consumers, and support programs related to women’s health, including the premenstrual syndrome.

The Asia-Pacific is expected to have positive market growth due to many females of childbearing age. There are growing government initiatives and campaigns for improving women and maternity health. For instance, India's National Health Portal creates awareness of women's health issues, including premenstrual syndrome. The rising expenditure for improving the healthcare facilities and infrastructure shall have a positive impact on the market. Substantial market growth is expected to be observed in developing countries, including India & China. 

Competitive Landscape

Bayer AG, Eli Lilly and Company, GlaxoSmithKline Plc, Pfizer Inc., H. Lundbeck A/S, Pfizer Inc., Asarina Pharma AB, Chattem, Inc. (Sanofi), Dekk-Tec, Pherin Pharmaceuticals, Novartis International AG are the leading market players with significant market share. The new product development, opportunity, and revenue generation shall intensify the market competition.

The companies use strategies such as collaborations, mergers, strategic partnerships, and acquisitions to hold their positions in the market. For instance, In Aug 2020, Bayer’s acquired KaNDy Therapeutics Limited to boost their female healthcare business.

Global Premenstrual Syndrome Treatment Market – Key Companies to Watch

Bayer AG:

Overview: Bayer is a biotech and pharmaceutical multinational company. It was founded in 1863 and is headquartered in Leverkusen, Germany. Their business area includes pharmaceutical, agriculture chemicals, healthcare products and biotechnology products.

Product Portfolio:

vissane: It is a progestin medication that is generally used in birth control pills and is used to treat heavy periods and for menopausal hormone.

Key Developments: In Aug 2020, Bayer’s acquired KaNDy Therapeutics Limited to boost their female healthcare business.

The global premenstrual syndrome treatment market report would provide an access to an approx. 45+market data table, 40+figures and 180pages.


Frequently Asked Questions

What is the Projected CAGR value of the Premenstrual Syndrome Treatment Market ?

Premenstrual Syndrome Treatment Market is expected to grow at a CAGR of 4.1% during the forecasting period 2022-2029.

Which region controlled the global market during 2022-2029?

North America region Controls the Premenstrual Syndrome Treatment Market  during 2022-2029.

Which is the fastest growing region in the Premenstrual Syndrome Treatment Market ?

Among all regions, Asia Pacific is the fastest growing market share during the forecast period.

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