Pazopanib API Market, Size, Share, Growth, Trends, Insight and Industry Forecast, 2021-2028

SKU: DMPH3615 | Last Updated On: Aug 31 2021 | No. of Pages: 180 | Available Formats

> Global Pazopanib API Market Expected to reach at a high CAGR by 2028: DataM Intelligence

Global Pazopanib API Market is segmented By Type: (Min Purity Less Than 98, Min Purity 98-99, Min Purity More Than 99), By Application (Research, Pharmaceutical), By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2021-2028

Market Overview

The pazopanib api Market The size was valued at US$ XX billion in 2020 and is estimated to reach US$ XX billion by 2028, growing at a CAGR of XX % during the forecast period (2021-2028). 

Pazopanib is an antineoplastic agent used to treat advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.

Source: DataM Intelligence Analysis (2020)

Market Dynamics

An increase in the incidence rate of cancer disease and the increase in advanced treatments will drive the pazopanib API Market

An increase in the incidence rate of renal cancer disease will drive the market

Renal cell cancer is also called kidney cancer or renal cell adenocarcinoma, disease in which malignant (cancer) cells are found in the lining of tubules in the kidney. RCC accounts for 2% of global cancer diagnoses and deaths, it has rapidly grown in incidence in the developed world, becoming the ninth most common cancer diagnosis in the US. RCC is the deadliest urological neoplasm and has a dismal late-stage, 5-year survival rate of 12%.

Pazopanib is an inhibitor of various tyrosine kinases, including vascular endothelial growth factor receptor and platelet-derived growth factor receptors. Pazopanib is involved in inhibiting signaling pathways, angiogenesis, and cell proliferation. It was approved by the US FDA and the European Medicines Agency at the dose of 800 mg daily. Pazopanib is effective in the treatment of metastatic RCC as reported.

An increase in the advanced treatments will drive the pazopanib API market

Pazopanib (Votrient(®)) is an orally administered multi-tyrosine kinase inhibitor approved in the EU, the US, and other countries to treat advanced renal cell carcinoma. VOTRIENT® (pazopanib) tablets are indicated to treat adults with advanced renal cell carcinoma (RCC). Monitor hepatic function and interrupt, reduce, or discontinue dosing as recommended. Over the last ten years, dramatic advances in the care of patients with advanced renal cell carcinoma have occurred, including insights into this disease's molecular pathogenesis, which have now been translated into paradigm-changing therapeutic strategies. The VEGF Receptor Tyrosine Kinase Inhibitor (VEGFR TKI) family of drugs grows and includes agents such as Sorafenib, Sunitinib, Axitinib, and Pazopanib. This class is broadly defined as small molecule inhibitors of the VEGF signaling cascade that exert their mechanism via the blockade of one or more VEGFR tyrosine kinases.

Side effects will hamper the pazopanib API market

Pazopanib side effects are easily predictable in terms of their onset, duration, and severity. They are almost reversible and will go away after therapy is complete. The common side effects of pazopanib are nausea, vomiting, diarrhea (which occurs in about half of patients), changes in hair colour, hypertension (which usually occurs during the first few weeks of treatment), appetite loss, hyperglycemia, hypoglycemia, electrolyte abnormalities (including hypocalcemia, hypomagnesemia, hypophosphatemia), laboratory anomalies (including increased AST, ALT, and protein in the urine), edema, hair loss or discoloration, change in the taste, abdominal pain, rash, fatigue and bone marrow suppression (including leucopenia, neutropenia, thrombocytopenia, and lymphopenia). Pazopanib has been associated with a low but real risk of potentially fatal liver damage.

COVID-19 Impact Analysis

COVID-19 has affected the healthcare industry. To curb its growth government completes a lockdown that stopped all industrial activities, hospital visits, and management of cancer patients. It also affected the pazopanib API market as the healthcare system focussed much on COVID-19 cases.

Market Segment Analysis

Minimum purity less than 98% will dominate the segment

Generally, the purity assessment of pharmaceutical grade materials involves structural characterization and the quantification of the impurities, frequently down to the 0.1% w/w level. Unless based on a specific rationale, purity thresholds of the general format >“X%” (e.g., “at least 99% pure” or “80% minimum purity”) commonly found in the journal, pharmacopoeial, and regulatory guidelines, as well as certificates of analysis, must be considered as arbitrary values.

The research segment will dominate the pazopanib API market in the forecast period

The research publications that review and collect the most relevant and important data help professionals involved in the management of patients and keep them informed of the latest developments, so literature reviews in oncology, as in other therapeutic areas are relevant and necessary. Whereas it is also known that real-world practice is much more complex and variable than the research environment

Pazopanib is a multikinase inhibitor that targets the VEGF receptor (VEGFR), the platelet-derived growth factor receptor (PDGFR), and c-Kit protein, inhibiting angiogenesis. It is used in adult patients with mRCC, both as a first-line treatment and after previous treatment with cytokines.Pazopanib hydrochloride which is an oral multi-targeted tyrosine kinase receptor inhibitor with anti-tumor activity. It inhibits vascular endothelial growth factor receptor (VEGFR)-1, -2, and-3, platelet-derived growth factor receptor (PDGFR), and ckit, resulting in inhibition of angiogenesis in tumors in which these receptors are up-regulated. Pazopanib hydrochloride is in phase II/III development for breast cancer and in phase II trials in patients with gynecological cancer,peritoneal cancer, nasopharyngeal cancer, non-small cell lung cancer, pancreatic cancer, soft tissue sarcoma, and glioma.

Geographical Analysis

North America will dominate the pazopanib API market

The strong focus of this region on its R&D, the availability of good healthcare infrastructure, increased renal cancer diseases, and timely approval of new products will increase its market in this region.

Globally, the incidence of renal cell carcinoma (RCC) widely varies from region to region, with the highest observed in the North America. In the U.S, there are approximately 76,000 new cases and almost 14,000 deaths from RCC each year. The American Cancer Society estimates that by 2021 there will be 76,080 cases (48,780 in males and 27,300 in females) of malignant tumors of the kidney and renal pelvis diagnosed, with 13,780 deaths (8790 in males and 4990 in females).

Total R&D expenditures at U.S. academic institutions reached $83.7 billion in FY 2019, an increase of almost $4.5 billion (5.7%) from FY 2018

Source: DataM Intelligence Analysis (2020)

Competitive Landscape

Major key players Tecoland, FCDA, BIOBERRY, Abcr, Dr. Reddys Laboratories, Pharmaffiliates, Jigs chemical, MuseChem, Hairuichem, Wuhan Fortuna Chemical, Shijiazhuang Dingmin Pharmaceutical Sciences, AlchemyPharm and Shanghai Pharmaceutical Group Co., Ltd., China Resources Pharmaceutical GroupCo., Ltd. and Guangzhou Baiyunshan Pharmaceutical Group Co., Ltd.

Pazopanib API Market Key Companies to Watch

Dr. Reddys Laboratories

Overview: Dr. Reddy’s Laboratories Ltd. is an integrated pharmaceutical company which is committed to provide affordable and innovative medicines for healthier lives. They have businesses of Pharmaceutical Services & Active Ingredients, Global Generics, and Proprietary Products. Their major therapeutic areas of focus are gastrointestinal, , diabetology, oncology, pain management, cardiovascular and dermatology. Dr. Reddy operates in markets across the globe. Our major markets include – USA, India, Russia & CIS countries, and Europe.

Product Portfolio: The company offers a portfolio of products and services, including APIs, custom pharmaceutical services, generics, biosimilars and differentiated formulations

Key Development: Dr. Reddy’s Laboratories has received the US Food and Drug Administration (FDA) approval for ELYXYB (celecoxib oral solution 25 mg/mL) to treat acute migraine with or without aura in adults.

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  • Visualize the composition of the Pazopanib API Market Segmentation By Type and By Application facility highlighting the key commercial assets and players.
  • Identify commercial opportunities in Pazopanib API Market by analyzing trends and co-development deals.
  • Excel data sheet with thousands of data points of Pazopanib API Market- level 4/5 segmentation.
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  • Product mapping in excel for the key product of all major market players

The Pazopanib API Market report would provide an access to an approx. 52 market data table, 40  figures and 200 pages. 

Target Audience

  • Service Providers/ Buyers
  • Industry Investors/Investment Bankers
  • Education & Research Institutes
  • Research Professionals
  • Emerging Companies
  • Manufacturers

Market Segmentation

Pazopanib API Market- By Type

  • Min Purity Less Than 98
  • Min Purity 98-99
  • Min Purity More Than 99

Pazopanib API Market- By Application

  • Research
  • Pharmaceutical

Pazopanib API Market- By Region

  • North America
  • Europe
  • South America
  • Asia Pacific
  • Middle East and Africa

Table of Contents

  1. Pazopanib API Market Methodology and Scope

    1. Research Methodology
    2. Research Objective and Scope of the Report
  2. Pazopanib API Market– Market Definition and Overview

  3. Pazopanib API Market– Executive Summary

    1. Market Snippet By Type
    2. Market Snippet By Application
  4. Pazopanib API Market– Market Dynamics

    1. Market Impacting Factors
      1. Drivers
        1. An increase in the incidence rate of renal cancer disease will drive the market
        2. An increase in the advanced treatments will drive the pazopanib API market
      2. Restraints:
        1. Side effects will hamper the pazopanib API market
      3. Opportunity
      4. Impact Analysis
  5. Pazopanib API Market– Industry Analysis

    1. Porter's Five Forces Analysis
    2. Epidemiology Analysis
    3. Supply Chain Analysis
    4. Pricing Analysis
    5. Regulatory Analysis
    6. Reimbursement Analysis
    7. Unmet Needs
  6. Pazopanib API Market– COVID-19 Analysis

    1. Analysis of Covid-19 on the Market
      1. Before COVID-19 Market Scenario
      2. Present COVID-19 Market Scenario
      3. After COVID-19 or Future Scenario
    2. Pricing Dynamics Amid Covid-19
    3. Demand-Supply Spectrum
    4. Government Initiatives Related to the Market During Pandemic
    5. Manufacturers Strategic Initiatives
    6. Conclusion 
  7. Pazopanib API Market– By Type:

    1. Introduction
      1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type Segment
      2. Market Attractiveness Index, By Type Segment
    2. Min Purity Less Than 98*
      1. Introduction
      2. Market Size Analysis, US$ Million, 2018-2028 and Y-o-Y Growth Analysis (%), 2020-2028
    3. Min Purity 98-99
    4. Min Purity More Than 99
  8. Pazopanib API Market– By Application:

    1. Introduction
      1. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application Segment
      2. Market Attractiveness Index, By Application Segment
    2. Research *
      1. Introduction
      2. Market Size Analysis, US$ Million, 2018-2028 and Y-o-Y Growth Analysis (%), 2020-2028
    3. Pharmaceutical
  9. Pazopanib API Market– By Region

    1. Introduction
      1. Market Size Analysis, US$ Million, 2018-2028 and Y-o-Y Growth Analysis (%), 2020-2028, By Region
      2. Market Attractiveness Index, By Region
    2. North America
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. U.S.
        2. Canada
        3. Mexico
    3. Europe
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. Germany
        2. U.K.
        3. France
        4. Italy
        5. Spain
        6. Rest of Europe
    4. South America
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. Brazil
        2. Argentina
        3. Rest of South America
    5. Asia Pacific
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
      5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
        1. China
        2. India
        3. Japan
        4. Australia
        5. Rest of Asia Pacific
    6. Middle East and Africa
      1. Introduction
      2. Key Region-Specific Dynamics
      3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Type
      4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
  10. Pazopanib API Market– Competitive Landscape

    1. Key Developments and Strategies
    2. Company Share Analysis
    3. Product Benchmarking
    4. List of Key Companies to Watch
    5. List of Company with disruptive technology
    6. List of Start Up Companies
  11. Pazopanib API Market- Company Profiles

    1. Dr. Reddys Laboratories*
      1. Company Overview
      2. Product Portfolio and Description
      3. Key Highlights
      4. Financial Overview
    2. Tecoland
    3. FCDA
    4. BIOBERRY
    5. Pharmaffiliates
    6. Jigs chemical
    7. MuseChem
    8. Hairuichem
    9. WUHAN FORTUNA CHEMICAL
    10. Huaian Meide Medical Instrument Co., Ltd.(LIST NOT EXHAUSTIVE)
  12. Pazopanib API Market– DataM  

    1. Appendix
    2. About Us and Services
    3. Contact Us

List of Tables & Figures

List of Tables

Table 01 Pazopanib API MarketValue, By Type , 2020, 2024 & 2028($ Million)

Table 02 Pazopanib API MarketValue, By Application, 2020, 2024 & 2028($ Million)

Table 03 Pazopanib API MarketValue, By Type, 2020, 2024 & 2028($ Million)

Table 04 Pazopanib API MarketValue, By Type, 2018-2028 ($ Million)

Table 05 Pazopanib API MarketValue, By Application, 2020, 2024 & 2028($ Million)

Table 06 Pazopanib API MarketValue, By Application, 2018-2028 ($ Million)

Table 07 Pazopanib API MarketValue, By Region, 2020, 2024 & 2028($ Million)

Table 08  Pazopanib API MarketValue, By Region, 2018-2028 ($ Million)

Table 09 North America Pazopanib API MarketValue, By Type, 2018-2028 ($ Million)

Table 10 North America Pazopanib API MarketValue, By Application, 2018-2028 ($ Million)

Table 11  North America Pazopanib API MarketValue, By Country, 2018-2028 ($ Million)

Table 12 South America Pazopanib API MarketValue, By Type, 2018-2028 ($ Million)

Table 13 South America Pazopanib API MarketValue, By Application, 2018-2028 ($ Million)

Table 14 South America Pazopanib API MarketValue, By Country, 2018-2028 ($ Million)

Table 15 Europe Pazopanib API MarketValue, By Type, 2018-2028 ($ Million)

Table 16 Europe Pazopanib API MarketValue, By Application, 2018-2028 ($ Million)

Table 17  Europe Pazopanib API MarketValue, By Country, 2018-2028 ($ Million)

Table 18 Asia-Pacific Pazopanib API MarketValue, By Type, 2018-2028 ($ Million)

Table 19 Asia-Pacific Pazopanib API MarketValue, By Application, 2018-2028 ($ Million)

Table 20 Asia-Pacific Pazopanib API MarketValue, By Country, 2018-2028 ($ Million)

Table 21 Middle East & Africa Pazopanib API MarketValue, By Type, 2018-2028 ($ Million)

Table 22 Middle East & Africa Pazopanib API MarketValue, By Application, 2018-2028 ($ Million)

Table 23 Dr. Reddys Laboratories: Overview

Table 24 Dr. Reddys Laboratories: Product Portfolio

Table 25 Dr. Reddys Laboratories: Key Developments

Table 26 Tecoland: Overview

Table 27 Tecoland: Product Portfolio

Table 28 Tecoland: Key Developments

Table 29 FCDA: Overview

Table 30 FCDA: Product Portfolio

Table 31 FCDA: Key Developments

Table 32 BIOBERRY: Overview

Table 33 BIOBERRY: Product Portfolio

Table 34 BIOBERRY: Key Developments

Table 35 Pharmaffiliates: Overview

Table 36 Pharmaffiliates: Product Portfolio

Table 37 Pharmaffiliates: Key Developments

Table 38 Jigs chemical: Overview

Table 39 Jigs chemical: Product Portfolio

Table 40 Jigs chemical: Key Developments

Table 41 MuseChem Overview

Table 42 MuseChem: Product Portfolio

Table 43 MuseChem: Key Developments

Table 44 Hairuichem: Overview

Table 45 Hairuichem: Product Portfolio

Table 46 Hairuichem: Key Developments

Table 47 WUHAN FORTUNA CHEMICAL: Overview

Table 48 WUHAN FORTUNA CHEMICAL: Product Portfolio

Table 49 WUHAN FORTUNA CHEMICAL: Key Developments

Table 50 Huaian Meide Medical Instrument Co., Ltd.: Overview

Table 51 Huaian Meide Medical Instrument Co., Ltd.: Product Portfolio

Table 52 Huaian Meide Medical Instrument Co., Ltd.: Key Developments

   List of Figures

Figure 01 Pazopanib API MarketShare, By  Type, 2020 & 2028(%)

Figure 02 Pazopanib API MarketShare, By Application, 2020 & 2028(%)

Figure 03 Pazopanib API MarketValue, 2018-2028 ($ Million)

Figure 04 Pazopanib API MarketY-o-Y Growth, By  Type, 2020-2028 (%)

Figure 05 Min Purity Less Than 98: Pazopanib API MarketValue, 2018-2028 ($ Million)

Figure 06 Min Purity 98-99: Pazopanib API MarketValue, 2018-2028 ($ Million)

Figure 07 Min Purity More Than 99: Pazopanib API MarketValue, 2018-2028 ($ Million)

Figure 08 Pazopanib API MarketY-o-Y Growth, By Application, 2020-2028 (%)

Figure 09 Research: Pazopanib API MarketValue, 2018-2028 ($ Million)

Figure 10 Pharmaceutical: Pazopanib API MarketValue, 2018-2028 ($ Million)

Figure 11  Pazopanib API MarketY-o-Y Growth, By Region, 2020-2028 (%)

Figure 12 North America Pazopanib API MarketValue, 2018-2028 ($ Million)

Figure 13 North America Pazopanib API MarketShare, By Type, 2020 & 2028(%)

Figure 14 North America Pazopanib API MarketShare, By Application, 2020 & 2028(%)

Figure 15 North America Pazopanib API MarketShare, By Country, 2020 & 2028(%)

Figure 16 South America Pazopanib API MarketValue, 2018-2028 ($ Million)

Figure 17  South America Pazopanib API MarketShare, By Type, 2020 & 2028(%)

Figure 18 South America Pazopanib API MarketShare, By Application, 2020 & 2028(%)

Figure 19 South America Pazopanib API MarketShare, By Country, 2020 & 2028(%)

Figure 20 Europe Pazopanib API MarketValue, 2018-2028 ($ Million)

Figure 21 Europe Pazopanib API MarketShare, By Type, 2020 & 2028(%)

Figure 22 Europe Pazopanib API MarketShare, By Application, 2020 & 2028(%)

Figure 23 Europe Pazopanib API MarketShare, By Country, 2020 & 2028(%)

Figure 24 Asia-Pacific Pazopanib API MarketValue, 2018-2028 ($ Million)

Figure 25 Asia-Pacific Pazopanib API MarketShare, By Type, 2020 &2028(%)

Figure 26 Asia-Pacific Pazopanib API MarketShare, By Application, 2020 & 2028(%)

Figure 27 Asia-Pacific Pazopanib API MarketShare, By Country, 2020 & 2028(%)

Figure 28 Middle East & Africa Pazopanib API MarketValue, 2018-2028 ($ Million)

Figure 29 Middle East & Africa Pazopanib API MarketShare, By Type, 2020 & 2028(%)

Figure 30 Middle East & Africa Pazopanib API MarketShare, By Application, 2020 & 2028(%)

Figure 31 Dr. Reddys Laboratories: Financials

Figure 32 Tecoland: Financials

Figure 33 FCDA: Financials

Figure 34 BIOBERRY: Financials

Figure 35 Pharmaffiliates: Financials

Figure 36 Jigs chemical: Financials

Figure 37 MuseChem Financials

Figure 38 Hairuichem: Financials

Figure 39 WUHAN FORTUNA CHEMICAL: Financials

Figure 40 Huaian Meide Medical Instrument Co., Ltd.: Financials

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