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Hunter Syndrome Treatment Market Size, Share, Industry, Forecast and outlook (2023-2030)

Published: 2023 June 12
SKU : PH1887
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180 pages
Report Summary
Table of Contents
List of Tables & Figures

Hunter Syndrome Treatment Market is segmented By Type (Enzyme Replacement Therapy (ERT), Hematopoietic Stem Cell Transplant (HSCT), others), By End User(Hospitals, Clinics, Specialty Care Unit), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2023-2030

 

Hunter Syndrome Treatment Market Outlook

(180 pages) Global Hunter Syndrome Treatment market to grow at a high CAGR Of 7% during the forecast period 2023- 2030. The market is expected to grow due to increasing demand from Hospitals, Clinics, Specialty Care Unit. The competitive rivalry intensifies with  ArmaGen, Takeda., Denali therapeutics, and others operating in the market.

 

As per DataM Intelligence, Hunter Syndrome Treatment Market study analysis offers an in-depth outlook on the market containing quantitative and qualitative data. It gives an outlook and forecast of the global market based on market segmentation. It also provides global Hunter Syndrome Treatment Market size, and growth, along with the latest trends, opportunities, and forecast till 2029 for the global market with esteem to major countries such as the United States, Canada, Brazil, Germany, Italy, Spain, United Kingdom, Russia, European countries, United Arab Emirates, Saudi Arabia, South Africa, Japan, China, India, South Korea, Australia, and rest of the countries over the globe.

Among all regions, the North American region is expected to hold the largest share of the global market over the forecast period. Hunter Syndrome Treatment Market in the United States and Canada produces the utmost share. Whereas the European Hunter Syndrome Treatment Market is projected to continue its presence globally during the period of 2023- 2030.

 

Hunter Syndrome Treatment Market Summary

Metrics

Details

Market CAGR

7%

Segments Covered

By Type, By End user, and By Region

Report Insights Covered

Competitive Landscape Analysis, Company Profile Analysis, Market Size, Share, Growth, Demand, Recent Developments, Mergers and acquisitions, New Product Launches, Growth Strategies, Revenue Analysis, and Other key insights.

Fastest Growing Region

Asia Pacific

Largest Market Share 

North America

 

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Hunter Syndrome Treatment Market Trends

The hunter syndrome treatment is driven by innovative novel therapies in clinical trials and increasing R&D activities to develop treatment.

Innovative novel therapies in clinical trials are expected to drive market growth.

The introduction of innovative treatments like gene therapy and RNA therapeutics is in great demand. Enzyme replacement therapy (ERT) with recombinant human I2S (idursulfase) is available for patients with Hunter syndrome. The U.S. Food and Drug Administration and the European Medicines Agency approved idursulfase for treating patients with Hunter syndrome based on a pivotal phase 2/3 randomized, double-blind, placebo-controlled clinical trial in 96 patients with Hunter syndrome aged 5–31 years. Stem Cell Transplant- In this, healthy blood cells are infused into your child’s body with the hope that the new cells will create the missing or defective enzyme. Gene Therapy-Replacing the chromosome responsible for producing the missing enzyme could theoretically cure Hunter syndrome, but much research needs to be done. However, research is still on for all these treatments.

The high cost of the treatment and lack of awareness among people are expected to hamper the market growth.

Though the treatment is rare, the treatment for the disorder is only available in U.S. and Europe and is very expensive, and there is no proper diagnosis. Many people are unaware of it. So, governments should create awareness about the disease and its treatment. The Lysosomal Storage Disorders Support Society (LSDSS), a non-profit organization working for several lysosomal disorders, said about 180 children with Hunter Syndrome are registered in India.

Industry Analysis

The hunter syndrome treatment market provides in-depth analysis of the market based on various industry factors such as epidemiology, unmet needs, pricing analysis, supply chain analysis, regulatory analysis etc.

 

COVID-19 Impact on Hunter Syndrome Treatment Market

The emergence of COVID-19 has impacted the whole world in some or another way. The health crisis has brought an unprecedented impact on businesses across industries. It has resulted in a decrease in public mobility, as well as impacted the diagnostic industries. Several diagnostic procedures and therapies were put on hold to avoid the spread of novel coronavirus.

 

Hunter Syndrome Treatment Market Segmentation Analysis

Enzyme Replacement Therapy segment is expected to hold the largest market share in the hunter syndrome treatment market.

The enzyme replacement therapy accounted for the largest market share in 2021. Hunter Syndrome is an X-linked lysosomal storage disorder due to the deficit of iduronate 2-sulfatase, an enzyme catalyzing the degradation of the glycosaminoglycans (GAG) dermatan- and heparan sulfate. The disease is mainly treated by Enzyme Replacement Therapy (ERT) with idursulfase, which has been used since 2006. Several products in ERT sales have significantly increased, which results in its growth. For instance, On January 22, 2021, GC Pharma (previously known as Green Cross Corporation) and Clinigen K.K. received manufacturing and marketing authorization for Hunterase ICV (intracerebroventricular) Injection of 15 mg (generic name: idursulfase-beta (recombinant)) as a therapy for mucopolysaccharidosis type II (Hunter syndrome). In Japan and other countries, an intravenous enzyme replacement medication is already used to treat the systemic symptoms of mucopolysaccharidosis type II. However, no therapeutic medication targets the central nervous system symptoms that affect around 70% of patients. Therefore, it has increased the demand for enzyme replacement therapy. Thus, from the above statements, the market segment accounted for the largest market share in the forecast period. ​ 

 

Hunter Syndrome Treatment Market Geographical Growth

North American region is expected to hold the largest market share in the global hunter syndrome treatment market.

North America dominates the global hunter syndrome treatment market. The higher diagnosis and treatment rates, a higher patient population and awareness of the treatment options. The presence of major clinical-stage biopharmaceutical companies as their pipeline candidates is responsible for the region's dominant share. For instance, Homology Medicines, Inc. completed a Phase 1 open-label, sequential ascending dose-escalation study in October 2022. This study aims to assess the safety and efficacy of a single IV infusion of the investigational gene therapy HMI-203. Males between the ages of 18 and 45 with MPS II (Hunter syndrome) who are currently taking idursulfase ERT (or the equivalent) are enrolled in the study. Thus, from the above statements, the North American region accounted for the largest market share in the forecast period.

 

Hunter Syndrome Treatment Market Company and Competitive Landscape

Major key players in the hunter syndrome treatment market are Denali Therapeutics Inc., Shire, AVROBIO, Green Cross Corporation, Takeda, Centogene AG Rostock, JCR Pharmaceuticals Co., Ltd., AVROBIO, ArmaGen, Inventiva and others.

Denali Therapeutics:

Overview:

Denali Therapeutics Inc. is a privately held biotechnology company focused on discovering and developing therapies for patients with neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, ALS, and others. Located in South San Francisco, investors share the vision that recent scientific insights in genetics, biology, and translational medicine offer an unprecedented opportunity to discover and develop effective medicines for neurodegenerative disease. Denali is rigorously pursuing a science-driven approach to translational medicine and clinical development.

­Pipeline Product:

U.S Food and Drug Administration (FDA) have granted Fast Track designation to ETV: IDS (DNL310) for the treatment of patients with Hunter syndrome (MPS II). DNL310, Denali’s lead investigational brain-penetrate enzyme replacement therapy, is under evaluation in a Phase 1/2 study in patients with Hunter syndrome as a potential treatment for both central nervous system (CNS) and peripheral manifestations of the disease. Using Denali’s transport vehicle technology, a company designed DNL310 to treat both body and brain in Hunter syndrome after intravenous administration.

 

The global hunter syndrome treatment market report would provide an access to an approx. 45+market data table, 40+figures and 180pages.

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FAQ’s
What is the Projected CAGR value of the Hunter Syndrome Treatment Market during the Forecast Period?
The Hunter Syndrome Treatment market is expected to grow at a CAGR of 7% during the forecast period.
Which region is expected to hold the largest market share in the global hunter syndrome treatment market?
North American region is expected to hold the largest market share in the global hunter syndrome treatment market.
Who are the leading end users for the global hunter syndrome treatment market?
The leading end users for the global hunter syndrome treatment market are Hospitals, Clinics, Specialty Care Unit.
Who are the Key players contributing to the market's growth?
The Key Players are Denali therapeutics, Shire, AVROBIO, Green Cross Corporation, Takeda, Centogene AG Rostock, JCR Pharmaceuticals Co., AVROBIO, ArmaGen, INVENTIVA.
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