Digital PCR Market size was valued US$ 613.81 million in 2021 and is estimated to reach US$ 1,259.9 million by 2029, growing at a CAGR of 7.4 % during the forecast period (2022-2029).
By Technology, By Product Type, By Application, By End-Users, and By Region
Report Insights Covered
Competitive Landscape Analysis, Company Profile Analysis, Market Size, Share, Growth, Demand, Recent Developments, Mergers and acquisitions, New Product Launches, Growth Strategies, Revenue Analysis, and Other key insights.
Fastest Growing Region
Largest Market Share
To Get a Free Sample Click here
The end-point PCR technique known as digital PCR is utilized for the accurate quantification and the study of small sequences in comparison to related large sequences. PCR stands for polymerase chain reaction. It amplifies the DNA or RNA segments multiple times. Finds genetic changes or infections in any individual.
The global digital PCR market is going to expand due to several factors some of them are rising technological advancements, novel product launch, growing incidents of infectious disease and surge in R&D activities by biopharma companies and increasing.
The increase in technological advancements and research & development by various biopharmaceutical companies is expected to drive market growth.
The surge in research and development activities by various major key players is major factor for driving the market. PCR is used to diagnose various illnesses, such as infectious disease as well as genetic changes. It can diagnose the disease in its earliest stage and. Even if only minute amounts of antibodies or cancer cells are present it can detect it by amplifying the DNA or RNA multiple times. Nucleic acid measurement is accurate and very sensitive thanks to digital PCR (dPCR). Traditional PCR uses agarose gel electrophoresis to detect the amplified product, making it a semi-quantitative end-point examination. The three main subtypes of digital PCR (dPCR) are beaming, droplet, and chip-based digital PCR.
One of the significant possibilities in the worldwide PCR market is the growth of R&D spending for d-PCR molecular diagnostics. In order to facilitate effective diagnosis, a number of biotech and life sciences businesses are collaborating on the development of diagnostic tests and the therapeutic use of d-PCR in a number of illness indications to provide effective treatment.
The introduction of new products by major companies together with technological breakthroughs in PCR technologies are fueling the market's expansion. For instance, some market participants have created unique dPCR products that can recognise various diseases or detect a variety of genetic abnormalities. Droplet Digital PCR SARS-CoV-2 Test Kit emergency use permission from the FDA was granted to Bio-Rad in 2020. For instance, in Mar 2021, Thermo Fisher announced United States Food and Drug Administration has completed the listing for QuantStudio 5, a real time PCR and launched it in the market. It helps labs and developers to fulfil the demands of testing.
Various major key players are developing latest products or models with novel technological innovations and advancements and most of the products receiving approval is fueling the market and will drive the growth of market. For instance, in 2020, Thermo Fisher created a number of PCR kits and tests for diagnostic and research used to fight the COVID-19 outbreak. They released AcroMetrix Coronavirus 2019 (COVID-19) RNA Control after receiving the US FDA's emergency use authorization (EUA) for the SARS CoV 2 multiplex real-time PCR test.
Technical limitations associated with the market are expected to hamper the market growth.
However, costly equipment and PCR's technological limitations are predicted to impede market expansion. A classic dPCR method is accompanied by a variety of technical limitations, including the need for assay procedure optimization and validation, the measurement of signals all through the exponential growth phase of the PCR amplification, difficulties in target detection caused by the existence of reaction modulators, and the inability to identify biomolecules due to the poor efficiency of the DNA sequence template. Additionally, the usage of carcinogenic chemicals, chemical binding of dPCR reagent to dsDNA and inability to evaluate DNA quality are some of the procedural restrictions that prevent the use of these reagents in genomic research.
The global digital PCR market provides in-depth analysis of the market based on various industry factors such as porter's five forces, unmet needs, supply chain analysis, regulatory analysis, pricing analysis etc.
COVID-19 Impact Analysis
The healthcare industry was severely impacted by the COVID-19 outbreak. The PCR market has experienced a boom, and the diagnosis sector was most severely affected. Real-time and digital PCR are in high demand since they are used for drug research and diagnostic purposes. It is becoming increasingly important for industry entities to test for COVID-19 by creating droplet digital PCR kits. The regulatory agencies have given these tests their full support in order to limit the COVID-19 pandemic's effects.
Since digital PCR techniques are utilized to diagnose COVID-19 infection, the COVID-19 epidemic is projected to positively affect the growth in the global PCR market. The market is expanding because COVID-19 infections are becoming more common.
Droplet digital PCR segment is expected to hold the largest market share in the global digital PCR market
The global digital PCR market is segmented into multiple segments on basis of technology, product, application and end-user.
The technology segment is further sub-segmented in droplet digital PCR, beaming digital PCR, and chip-based digital PCR. Droplet digital PCR is expected to hold the largest market share due to the increasing number of product launches and various novel technological advances. Nucleic acid analysis can be done with extreme sensitivity and precise precision because to the development of digital PCR. It is also helpful for monitoring low-abundance targets, allelic variations (SNPs), targets with complicated backgrounds, and tiny changes in target levels that real-time PCR is unable to pick up on. The use of this technology in vitro testing has now been authorized.
The droplet digital PCR divides the sample of DNA into 20,000 droplets using water-emulsion droplet technology. Every particular droplet then experiences PCR replication of the template and quantifying the positive droplets provides accurate target estimation. Absolute quantification, high precision, and high sensitivity can be seen in droplet digital PCR so it will be more helpful and accurate for analysis. For instance, in 2020, Bio-Rad announced that the droplet digital PCR SARS-CoV-2 test kit got emergency use permission from the United States Food and Drug Administration for COVID testing.
The end-user segment is also going to see the fastest growth in the forecast period due to the rising incidence of infectious disease and novel viruses and their variants. Recently SARS COV caused a pandemic and during that time PCR was widely used globally for diagnosis purposes. A significant increase in the demand for PCR by all the diagnostic centers, hospitals, and research institutes impacted the PCR market positively and drove its growth of the market. Now digital PCR is in demand as it is reliable, flexible, simple and more efficient to operate and provides results accurately leading to the growth of the market.
North America region holds the largest market share in the global digital PCR market
In 2021 North America reserve the extensive share in digital PCR market, and it is estimated that it is also going to overshadow the global market in the coming years owing to upsurge in widespread presence of chronic diseases, existence of key players for the progress of digital PCR devices, and prevalent foundation and substructure in the region. The growing technological advancement for the development of digital PCR products shall stimulate the market. The presence of favorable reimbursement policies and better healthcare facilities shall fuel the market growth.
Most of the key players are present in this region such as Thermo Fisher Scientific, Bio-Rad Laboratories Inc., Becton, Dickinson and Company and F. Hoffmann-La Roche, Ltd. All of them are launching various innovative and novel products. Various acquisitions and merges are also taking place hence fueling the growth of market in this particular region and making North America the largest shareholder.
Because of the continuing expansion and upgrading of the medical infrastructure in developing Asian nations, the rise in the number of genomics and oncology research projects carried out in India, and Japan, the rising tendency of medical research to become outsourced to Asia by top drug manufacturing companies, and ongoing government assistance for genomics-based initiatives, the Asia Pacific market is expected to expand at the highest CAGR throughout the forecast period. The growing technological advancement, rising healthcare investment, and increasing research and development activities shall also stimulate market growth.
The global digital PCR market is highly competitive with the presence of several international and local markets. Product diversification, revenue generation, and opportunities intensify the market competition. Thermo Fisher Scientific, Bio-Rad Laboratories Inc., and F. Hoffmann-La Roche, Ltd. are the three prime key players operating in global digital PCR market. Other well-known players are Agilent Technologies, Abbott Laboratories, Becton Dikinson and Company, Danaher Corporation, Eppendorf, Merck KGaA, Promega Corporation, Takara Bio, Enzo Life Sciences, Meridian Bioscience, Bioneer, QIAGEN N.V, ELITech Group, Genetron Holdings Limited.
The companies are entering into collaborations, strategic partnerships, acquisitions and mergers to increase the demand for digital PCR and their expansion across the globe. In Sep 2020, Qiagen announced its partnership with NeuMoDx. Both are going to work on manufacturing and commercializing automated fully integrated PCR devices.
Companies are using the new product launch, product development, market expansion, and technological advancement strategies for holding their market position. For instance, in Sep 2022, Thermo Fisher certified its Applied Biosystems QuantStudio 7 Pro Dx, a real time PCR as it fulfils all the requirements by novel in-vitro medical devices regulation. Now it includes biosystem Diomni Software ecosystem to grant labs and developers of test to support the flexible PCR testing.
In Sep 2022, Qiagen announced novel additions in their NeuMoDx assay portfolio for the viruses associated with the organ transplant. Its latest assays got CE-In Vitro Diagnostic mark for European Union and various other countries. The novel assays are for identifying and quantifying human herpes virus 6 and Epstein barr virus.
In May 2022, Qiagen launched therascreen EGFR Plus RGQ PCR kit. It is the novel test kit for in-vitro diagnostic for analysis of EGFR mutation as it detects all the activating EGFR mutations and resistance EGFR mutations. This device provides better detection limits, automatic sample extraction and automatic analysis of results.
Global Digital PCR Market – Key Companies to Watch
Thermo Fisher Scientific:
Overview: Thermo Fisher Scientific is a healthcare distributor company that serves science. They manufacture and markets reagents, scientific instruments & equipment, consumables, and software service. It was established in 1956 and is based in Walttham, Massachusetts, United States.
QuantStudio 6 and 7 Pro Real-Time PCR Systems- These are PCR systems that are very flexible as they reinforce various kinds of applications and favorable conditions. The smart of these systems are created to minimise tontamination by making it rthem hands-free. Mobile phones can be used to schedule and even monitor the run. The QuantStudio 6 and 7 Pro systems contains 96-well blocks that comprises a technology that is known as VeriFlex that is used for specific temperature control. All these blocks are prorated into secluded zones due to which there are separate cycling surrounding inside the one and same run that is ideal for optimization.
Key Developments: In Feb 2022, Therma Fisher launched its rapid Renvo PCR test to fight with COVID-19. It is a novel solution in-air product that is included in its portfolio of pathogen surveillance. This test is done on the air samples that are collected by aerosol sense sampler.
The digital PCR market report would provide an access to an approx. 45+market data table, 40+figures and 180pages.
What is the Projected CAGR value of the Digital PCR Market?
Digital PCR Market is expected to grow at a CAGR of 12.9% during the forecasting period 2022-2029.
Which region controlled the global market during 2022-2029?
North America region Controls the Digital PCR Market during 2022-2029
Which is the fastest growing region in the Digital PCR Market?
Among all regions, Asia Pacific is the fastest growing market share during the forecast period
Get your free sample proposal with a single click!