Electroporation Instruments and Consumables Market. DataM Intelligence

Development of vaccine delivery system using electroporation technology

The electroporation technique is widely preferred to enhance nucleic acid uptake with the DNA to generate an immune response against an antigen when the vaccine is delivered through the skin. The rise in the prevalence of infectious diseases and other skin disorders is likely to drive the demand for electroporation instruments and consumables. 

The potential of the electrophoresis method in locating the local antigen expression in the epidermis offers a significant advantage to patients. 

Electroporation technique creates an inflammatory environment, and hence, its association with DNA vaccination would result in strong expression of vaccine antigen, thus driving the global electroporation instruments and consumables market.

Moreover, extensive portfolios for a range of electroporation products offered by the major and the emerging players are stimulating the growth of the market. Several advantages provided by the method like the ease of use, variability, and timeliness are escalating the growth of the segment. 

For instance, on November 09, 2018 CRISPR Therapeutics and MaxCyte announced the expansion of the existing relationship by entering into a non-exclusive commercial license agreement which allows the CRISPR Therapeutics to deploy the MaxCyte’s Flow Electroporation® Technology to develop CRISPR/Cas9-based therapies in immuno-oncology. Thus, the presence of extensive product portfolios and the added advantages of the electroporation are driving the market. 

Progress in gene editing techniques

The advancements in gene-editing technologies, including regularly- interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins or transcription activator-like effector nucleases (TALENs), have enabled the researchers to curate targeted sequence-specific changes across the DNA– a factor that is expected to rise the adoption of electroporation instruments. 

As the advancements in gene-editing techniques occur at a steady pace, the prospects of this market continue to look at a bright future.

Moreover, as applications of gene editing techniques continue to increase research and development, the adoption of electroporation instruments is likely to witness considerable growth. 

In addition, significant advancements in the electroporation instruments and electrodes coupled with the increasing compatibility with cutting-edge gene-editing technology are likely to play a key role in the overall development of the global electroporation instruments and consumables market.

In June 2018, the first genome editing method for R. eutropha using an electroporation-based CRISPR-Cas9 approach was presented in a research paper. This method significantly increased the efficiency and decreased time to manipulate this facultative chemolithoautotrophic microbe. The novel technique will facilitate more advanced research and applications of R. eutropha for PHA production and CO2 conversion.

Development of new technological instruments

• New technologies have paved the way for the introduction of cutting-edge medical devices to be employed to treat a wide range of medical diseases and conditions.
• Various market participants have invested in the creation of novel techniques due to ongoing breakthroughs in the development of novel products for transient and stable transfection with low off-target effects., thus providing opportunities.
• The Ohio State University Wexner Medical Center and the Ohio State College of Engineering collaborated in August 2017 to create a TNT technology that can mend tissues and rejuvenate ageing cells.
• TNT was employed by Ohio State University researchers to treat car accident victims and injured troops. One of the primary drivers boosting the market for electroporation instruments and consumables is the integration of nanotechnology with transfection.

Increasing approval rates and growing adoption in developed regions

• Developed regions, including North America and Europe are expected to provide lucrative growth opportunities to the players involved in the current electroporation instruments and consumables market landscape. 
• The advanced healthcare infrastructure is expected to play an imperative role in boosting the growth of the electroporation instruments and consumables market in these regions. 
• Moreover, the rate of approval of electroporation instruments in Europe and North America is higher than in Asia Pacific.
• Furthermore, as electroporation continues to gain traction in Europe as a result of increased authorization for the clinical use of electro chemotherapy, market players are likely to focus on tapping into the opportunities across the European Union.

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