Cracking The Viral Vector Manufacturing Market Code

Pandemic has poses high risk to the patients suffering from Kidney disease and going through peritoneal dialysis

The pandemic of novel coronavirus disease 2019 (COVID-19) is posing a threat to all populations, especially those with underlying diseases kidney diseases. As per Johns Hopkins University stated that some people with COVID-19 are showing signs of kidney damage, even those who had no underlying kidney problems before they were infected with the coronavirus. Moreover, about 30% of patients hospitalized with COVID-19 in New York and China developed moderate or severe kidney injury. 

In patients with COVID-19, signs of kidney problems include abnormal blood work and high levels of protein in the urine which may lead to kidney damage in some cases and require peritoneal dialysis.

In addition, as per National Kidney Foundation Inc., in 2020, stated that people who are on peritoneal dialysis treatment may be at higher risk for severe disease from COVID-19. For severe cases, patient recovery may take 6 weeks or more. Further, about 1% of patients who are infected will die from the disease.

According to a research article by Claudia Benedetti et al., published in Frontiers in Medicine Journal 2020, the study results indicate that patients with kidney disease could represent a risk factor in elderly patients, for a more severe disease course. COVID-19 infects the kidneys and may induce acute kidney injury. 

Furthermore, in the United States, patients with pre-existing chronic kidney disease (CKD) were considered to be largely susceptible to COVID-19. For instance, a research article by Jennifer E Flythe et al, published in the American Journal of Kidney Diseases 2020, stated that high mortality can be observed in patients with underlying kidney disease and severe COVID-19.

Pandemic has created opportunity for the market

Patients are seen less frequently, limiting the close interaction between patients and healthcare workers who may contract and spread the disease. However, while home dialysis is a reasonable choice at this time due to the advantage of isolation of patients, measures must be assured to implement the program. 

This is reflected in the data relating to COVID-19 infection being collected prospectively by the United Kingdom Renal Registry and the Ontario Renal Network. In the United Kingdom, by April 29, 2020, 2.9% of patients on PD were reported to have contracted COVID-19 compared with 9% of patients on hemodialysis.

Two ESKD health care reform initiatives in the United States have increased support for home-based dialysis, which may prove useful in reducing risks presented by the COVID-19 pandemic. The first, the ESKD Prospective Payment System, created a favorable reimbursement structure that has realized increasing use of home-based dialysis in the United States. 

Given the lower risk of COVID-19 exposure from home-based dialysis compared with in-center dialysis, enabling more patients to undergo dialysis at home will protect individuals from COVID-19-related morbidity and mortality and will help limit spread of infection into the community. Studies already show a strong association between appropriate education and the proportion of patients who subsequently choose PD. 

The “stay-at-home” messages related to the pandemic are likely to further increase this choice. Because both COVID-19 mortality and the need for maintenance dialysis increase with age, older patients are particularly going to benefit from dialysis at home.

But it is precisely these individuals who have been less likely to receive home dialysis than in-center hemodialysis in the United States. In the United Kingdom and Canada, assistance is available for older people to have PD in their home or nursing homes.

Studies show that patient satisfaction is higher for assisted PD compared with in-center hemodialysis. Ensuring patients receive education about PD and exploring models of providing assistance that may also include reimbursement to family care partners seem likely to increase PD eligibility and use.

Supporting growth in PD will require increasing resources for PD catheter placement to make this procedure available in the setting of COVID-19. It is also important to ensure universal availability of both surgical and percutaneous approaches for PD catheter insertion. In many regions, the demand for ventilators, operating room closures, and the risk of aerosol spray associated with laparoscopic procedures for PD catheter placement have curtailed access to surgery. 

PD can be monitored remotely by telephone

COVID-19 resilience also includes developing robust telemedicine strategies that minimize in-person interactions with healthcare. Experience from the COVID-19 pandemic so far has shown that patients using PD can be monitored remotely by telephone, with or without video. Those on automated PD can take advantage of the remote monitoring technology that is now available on many automated PD cyclers, enabling PD teams to monitor dialysis performance and change the prescription remotely if needed.

Temporary regulatory concessions to enhance greater use of telemedicine during the COVID-19 pandemic should prompt consideration of a long-term shift to telehealth among patients receiving home dialysis, with a critical evaluation of this approach’s effect on patient-reported and clinical outcomes. Recently updated International Society for Peritoneal Dialysis guidelines for prescribing PD have stated that the prescription should focus on the patient’s well-being and enable achievement of the patient’s goals, de-emphasizing small-solute clearance alone as a measure of high-quality dialysis. 

About Us:

DataM Intelligence was incorporated in the early weeks of 2017 as a Market Research and Consulting firm with just two people on board. Within a span of less than a year, we have secured more than 100 unique customers from established organizations all over the world.

For more information:

Sai Kiran

Sales Manager at DataM Intelligence

Email: [email protected]

Tel: +1 877 441 4866

Website: www.datamintelligence.com